Lineage for Superfamily d.4.1: His-Me finger endonucleases

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2927847Fold d.4: His-Me finger endonucleases [54059] (1 superfamily)
    core: (alpha)-beta-omega_loop-beta-alpha; embeded in larger different structures
  4. 2927848Superfamily d.4.1: His-Me finger endonucleases [54060] (8 families) (S)
    common motif contains conserved histidine residue and metal-binding site

Families:

  1. 2927849d.4.1.1: HNH-motif [54061] (3 proteins)
  2. 2927914d.4.1.2: DNA/RNA non-specific endonuclease [54066] (2 proteins)
    the core motif is inserted in a six-stranded meander beta-sheet domain
    automatically mapped to Pfam PF01223
  3. 2927931d.4.1.3: Intron-encoded homing endonucleases [54069] (2 proteins)
  4. 2927955d.4.1.5: Recombination endonuclease VII, N-terminal domain [68915] (1 protein)
  5. 2927968d.4.1.6: Endonuclease I [102726] (2 proteins)
    automatically mapped to Pfam PF04231
  6. 2927986d.4.1.7: Caspase-activated DNase, CAD (DffB, DFF40) [110778] (1 protein)
  7. 2927990d.4.1.8: HNH domain from CRISPR-associated protein Cas9 [345970] (1 protein)
    Homology to HNH nucleases noted in PubMed 21756346
    Pfam PF13395
  8. 2928000d.4.1.0: automated matches [273673] (1 protein)
    not a true family

More info for Superfamily d.4.1: His-Me finger endonucleases

Timeline for Superfamily d.4.1: His-Me finger endonucleases: