Lineage for Protein: (Pro)cathepsin K

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2154577Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 2154578Superfamily d.3.1: Cysteine proteinases [54001] (24 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 2154579Family d.3.1.1: Papain-like [54002] (26 protein domains)
  6. 2154605Protein (Pro)cathepsin K [54028] (3 species)

Species:

  1. 2154606Human (Homo sapiens) [TaxId:9606] [54029] (51 PDB entries)
    Uniprot P43235 116-329 ! Uniprot P43235 115-329
    1. Domain for 1atk:
    2. Domain for 1au0:
    3. Domain for 1au2:
    4. Domain for 1au3:
    5. Domain for 1au4:
    6. Domain for 1ayu:
    7. Domain for 1ayv:
    8. Domain for 1ayw:
    9. Domain for 1bgo:
    10. Domain for 1by8:
    11. Domain for 1mem:
    12. Domains for 1nl6:
      1. 2154659Domain d1nl6a_: 1nl6 A: [80619]
        complexed with 750
      2. 2154660Domain d1nl6b_: 1nl6 B: [80620]
        complexed with 750
    13. Domains for 1nlj:
      1. 2154651Domain d1nlja_: 1nlj A: [80626]
        complexed with 2ca
      2. 2154652Domain d1nljb_: 1nlj B: [80627]
        complexed with 2ca
    14. Domain for 1q6k:
    15. Domain for 1snk:
    16. Domains for 1tu6:
      1. 2154612Domain d1tu6a_: 1tu6 A: [107318]
        complexed with fsp, so4
      2. 2154613Domain d1tu6b_: 1tu6 B: [107319]
        complexed with fsp, so4
    17. Domain for 1u9v:
    18. Domain for 1u9w:
    19. Domain for 1u9x:
    20. Domain for 1vsn:
    21. Domain for 1yk7:
    22. Domain for 1yk8:
    23. Domain for 1yt7:
    24. Domain for 2ato:
    25. Domain for 2aux:
    26. Domain for 2auz:
    27. Domain for 2bdl:
    28. Domain for 2fdz:
    29. Domains for 2ftd:
      1. 2154649Domain d2ftda_: 2ftd A: [134058]
        automated match to d2r6na1
        complexed with ili
      2. 2154650Domain d2ftdb_: 2ftd B: [134059]
        automated match to d2r6na1
        complexed with ili
    30. Domain for 2r6n:
    31. Domain for 3c9e:
    32. Domain for 3kw9:
    33. Domains for 3kwb:
      1. 2154626Domain d3kwbx_: 3kwb X: [199680]
        automated match to d1tu6a_
        complexed with orh
      2. 2154627Domain d3kwby_: 3kwb Y: [191890]
        automated match to d2r6na1
        complexed with orh
    34. Domain for 3kwz:
    35. Domain for 3kx1:
    36. Domain for 3o0u:
    37. Domain for 3o1g:
    38. Domain for 3ovz:
    39. Domain for 4dmx:
    40. Domains for 4dmy:
      1. 2154609Domain d4dmya_: 4dmy A: [192344]
        automated match to d2r6na1
        complexed with 0lc, gol, so4
      2. 2154610Domain d4dmyb_: 4dmy B: [192345]
        automated match to d2r6na1
        complexed with 0lc, gol, so4
    41. Domain for 4n79:
    42. Domain for 4n8w:
    43. Domain for 4x6h:
    44. Domain for 4x6i:
    45. Domain for 4x6j:
    46. Domain for 4yv8:
    47. Domain for 4yva:
    48. Domain for 5jh3:
    49. Domain for 5tdi:
    50. Domain for 5tun:
    51. Domains for 7pck:
      1. 2154654Domain d7pcka_: 7pck A: [37079]
        contains propeptide
      2. 2154655Domain d7pckb_: 7pck B: [37080]
        contains propeptide
      3. 2154656Domain d7pckc_: 7pck C: [37081]
        contains propeptide
      4. 2154657Domain d7pckd_: 7pck D: [37082]
        contains propeptide
  2. 2154662Rabbit (Oryctolagus cuniculus) [TaxId:9986] [142845] (1 PDB entry)
    Uniprot P43236 115-329
  3. 2285440Mus musculus [TaxId:10090] [328741] (1 PDB entry)

More info for Protein (Pro)cathepsin K from d.3.1.1: Papain-like

Timeline for Protein (Pro)cathepsin K from d.3.1.1: Papain-like: