SCOP 1.73: Protein: Hydroxyethylthiazole kinase (THZ kinase, ThiK)

Lineage for Protein: Hydroxyethylthiazole kinase (THZ kinase, ThiK)

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.72: Ribokinase-like [53612] (3 superfamilies)
core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
potential superfamily: members of this fold have similar functions but different ATP-binding sites

Superfamily c.72.1: Ribokinase-like [53613] (5 families)
has extra strand located between strands 2 and 3
Family c.72.1.2: Thiamin biosynthesis kinases [53620] (2 proteins)
Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) [53621] (2 species)

Species:

Archaeon Pyrococcus horikoshii [TaxId:53953] [102637] (1 PDB entry)
- Domain for 1v8a:
  - Domain d1v8aa_: 1v8a A: [100494]
    complexed with cl, zn
Bacillus subtilis [TaxId:1423] [53622] (5 PDB entries)
1. Domains for 1c3q:
  1. Domain d1c3qa1: 1c3q A:1-272 [118436]
  2. Domain d1c3qb1: 1c3q B:1-272 [118437]
  3. Domain d1c3qc1: 1c3q C:1-272 [118438]
    complexed with cl, tze
2. Domains for 1ekk:
  1. Domain d1ekka_: 1ekk A: [34946]
  2. Domain d1ekkb_: 1ekk B: [34947]
    complexed with so2, tze; mutant
3. Domains for 1ekq:
  1. Domain d1ekqa_: 1ekq A: [34941]
  2. Domain d1ekqb_: 1ekq B: [34942]
    mutant
4. Domains for 1esj:
  1. Domain d1esja1: 1esj A:1-272 [34943]
  2. Domain d1esjb1: 1esj B:1-272 [34944]
  3. Domain d1esjc1: 1esj C:1-272 [34945]
    complexed with so4; mutant
5. Domains for 1esq:
  1. Domain d1esqa1: 1esq A:1-272 [34951]
  2. Domain d1esqb1: 1esq B:1-271 [34952]
  3. Domain d1esqc1: 1esq C:1-272 [34953]
    complexed with atp, mg, so4, thq; mutant

More info for Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases

Timeline for Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases:

Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases first appeared (with stable ids) in SCOP 1.55, called Protein Hydroxyethylthiazole kinase (thz kinase) from c.72.1.2: Hydroxyethylthiazole kinase (thz kinase)
Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases appears in SCOP 1.71
Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases appears in SCOP 1.75
Protein Hydroxyethylthiazole kinase (THZ kinase, ThiK) from c.72.1.2: Thiamin biosynthesis kinases appears in the current release, SCOPe 2.08