SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.72.1.1: Ribokinase-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2137471Fold c.72: Ribokinase-like [53612] (3 superfamilies)
    core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
    potential superfamily: members of this fold have similar functions but different ATP-binding sites
  4. 2137472Superfamily c.72.1: Ribokinase-like [53613] (6 families) (S)
    has extra strand located between strands 2 and 3
  5. 2137473Family c.72.1.1: Ribokinase-like [53614] (10 protein domains)
    automatically mapped to Pfam PF00294

Protein Domains:

  1. 21374742-keto-3-deoxygluconate kinase [75295] (2 species)
    1. 2137475Species Thermotoga maritima, TM0067 [TaxId:2336] [75296] (2 PDB entries)
    2. 2137480Species Thermus thermophilus [TaxId:274] [102640] (4 PDB entries)
  2. 2137495Adenosine kinase [53617] (3 species)
    1. 2137496Species Human (Homo sapiens) [TaxId:9606] [53618] (4 PDB entries)
    2. 2137506Species Toxoplasma gondii [TaxId:5811] [53619] (13 PDB entries)
    3. 2291749Species Mus musculus [TaxId:10090] [335051] (2 PDB entries)
  3. 2137520Aminoimidazole riboside kinase [117720] (1 species)
  4. 2137528Fructose 1-phosphate kinase FruB [142712] (1 species)
  5. 2137531Hypothetical fructokinase ST2478 [142714] (1 species)
  6. 2137534Hypothetical protein TM0415 [102641] (1 species)
  7. 2137537Putative sugar kinase TM0828 [82518] (1 species)
  8. 2137541Ribokinase [53615] (3 species)
    1. 2137542Species Escherichia coli [TaxId:562] [53616] (5 PDB entries)
    2. 2137554Species Human (Homo sapiens) [TaxId:9606] [142709] (9 PDB entries)
      Uniprot Q9H477 15-322
    3. 2137557Species Thermotoga maritima [TaxId:2336] [110706] (1 PDB entry)
      Uniprot Q9X055
  9. 2137560Tagatose-6-phosphate kinase LacC [142710] (1 species)
  10. 2137563automated matches [190470] (2 species)
    not a true protein
    1. 2137564Species Bacillus halodurans [TaxId:86665] [187390] (1 PDB entry)
    2. 2137566Species Sulfolobus solfataricus [TaxId:2287] [188040] (2 PDB entries)

More info for Family c.72.1.1: Ribokinase-like

Timeline for Family c.72.1.1: Ribokinase-like: