SCOPe 2.02: Family c.69.1.14: Carboxylesterase/thioesterase 1

Lineage for Family c.69.1.14: Carboxylesterase/thioesterase 1

1. Root: SCOPe 2.02

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.14: Carboxylesterase/thioesterase 1 [53547] (5 proteins)

Proteins:

1. Acyl protein thioesterase 1 [53550] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [53551] (1 PDB entry)

2. Carboxylesterase [53548] (2 species)

   1. Species Bacillus cereus [TaxId:1396] [159737] (1 PDB entry)
      Uniprot Q81AD5 1-202
      similar fold and function to the Pseudomonas fluorescens enzyme despite low sequence identity

   2. Species Pseudomonas fluorescens [TaxId:294] [53549] (2 PDB entries)

3. Uncharacterized protein Atu2452 [159740] (1 species)

   • Species Agrobacterium tumefaciens [TaxId:358] [159741] (1 PDB entry)
     Uniprot A9CHT9 1-203

4. Uncharacterized protein Mll8374 [159738] (1 species)

   • Species Mesorhizobium loti [TaxId:381] [159739] (1 PDB entry)
     Uniprot Q983D6 7-215

5. automated matches [191018] (1 species)
   not a true protein

   • Species Pseudomonas aeruginosa [TaxId:287] [188798] (2 PDB entries)

More info for Family c.69.1.14: Carboxylesterase/thioesterase 1

Timeline for Family c.69.1.14: Carboxylesterase/thioesterase 1:

• Family c.69.1.14: Carboxylesterase/thioesterase 1 first appeared (with stable ids) in SCOP 1.55
  
• Family c.69.1.14: Carboxylesterase/thioesterase 1 appears in SCOPe 2.01
  
• Family c.69.1.14: Carboxylesterase/thioesterase 1 appears in SCOPe 2.03
  
• Family c.69.1.14: Carboxylesterase/thioesterase 1 appears in the current release, SCOPe 2.08