Lineage for Superfamily c.69.1: alpha/beta-Hydrolases

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 400671Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 400672Superfamily c.69.1: alpha/beta-Hydrolases [53474] (30 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9

Families:

  1. 400673c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)
  2. 400794c.69.1.2: Carboxylesterase [53487] (4 proteins)
  3. 400821c.69.1.3: Mycobacterial antigens [53491] (3 proteins)
  4. 400835c.69.1.4: Prolyl oligopeptidase, C-terminal domain [53496] (1 protein)
    N-terminal domain is a 7-bladed beta-propeller
  5. 400852c.69.1.5: Serine carboxypeptidase-like [53499] (3 proteins)
  6. 400873c.69.1.6: Gastric lipase [53506] (1 protein)
  7. 400881c.69.1.7: Proline iminopeptidase-like [53509] (3 proteins)
  8. 400894c.69.1.8: Haloalkane dehalogenase [53513] (1 protein)
  9. 400929c.69.1.9: Dienelactone hydrolase [53518] (1 protein)
  10. 400935c.69.1.10: Carbon-carbon bond hydrolase [53522] (3 proteins)
    closely related to the Proline iminopeptidase-like family
  11. 400948c.69.1.11: Epoxide hydrolase [53525] (2 proteins)
  12. 400971c.69.1.12: Haloperoxidase [53531] (6 proteins)
  13. 401000c.69.1.13: Thioesterases [53542] (3 proteins)
  14. 401013c.69.1.14: Carboxylesterase/thioesterase 1 [53547] (2 proteins)
  15. 401024c.69.1.15: A novel bacterial esterase [53552] (1 protein)
  16. 401029c.69.1.16: Lipase [53555] (1 protein)
  17. 401034c.69.1.17: Fungal lipases [53558] (3 proteins)
  18. 401107c.69.1.18: Bacterial lipase [53570] (3 proteins)
    lack the first two strands of the common fold
  19. 401140c.69.1.19: Pancreatic lipase, N-terminal domain [53577] (1 protein)
  20. 401158c.69.1.20: Hydroxynitrile lyase [53585] (1 protein)
  21. 401184c.69.1.21: PepX catalytic domain-like [69581] (3 proteins)
  22. 401205c.69.1.22: Thioesterase domain of polyketide synthase [69584] (3 proteins)
  23. 401225c.69.1.23: Ccg1/TafII250-interacting factor B (Cib) [75285] (1 protein)
  24. 401229c.69.1.24: Dipeptidyl peptidase IV/CD26, C-terminal domain [82497] (1 protein)
    N-terminal domain is a 8-bladed beta-propeller
  25. 401251c.69.1.25: Acetyl esterase (deacetylase) [82504] (1 protein)
  26. 401266c.69.1.26: Biotin biosynthesis protein BioH [82509] (1 protein)
  27. 401270c.69.1.27: Hypothetical protein TT1662 [102616] (1 protein)
  28. 401279c.69.1.28: Aclacinomycin methylesterase RdmC [102620] (1 protein)
  29. 401284c.69.1.29: Carboxylesterase [102623] (1 protein)
  30. 401289c.69.1.30: Cutinase-like [52260] (2 proteins)
    minimal alpha/beta hydrolase lacking peripheral secondary structures; similar to a flavodoxin-like fold

More info for Superfamily c.69.1: alpha/beta-Hydrolases

Timeline for Superfamily c.69.1: alpha/beta-Hydrolases: