SCOPe 2.01: Family c.67.1.4: GABA-aminotransferase-like

Lineage for Family c.67.1.4: GABA-aminotransferase-like

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.4: GABA-aminotransferase-like [53417] (17 proteins)
   formerly omega-Aminoacid:pyruvate aminotransferase-like

Proteins:

1. 1-aminocyclopropane-1-carboxylate synthase (ACC synthase) [53440] (2 species)

   1. Species Apple (Malus domestica) [TaxId:3750] [53441] (5 PDB entries)

   2. Species Tomato (Lycopersicon esculentum) [TaxId:4081] [64130] (2 PDB entries)

2. 2-amino-3-ketobutyrate CoA ligase [64128] (1 species)

   • Species Escherichia coli [TaxId:562] [64129] (1 PDB entry)

3. 3-amino-5-hydroxybenzoic acid synthase (AHBA synthase) [53434] (1 species)

   • Species Amycolatopsis mediterranei [TaxId:33910] [53435] (2 PDB entries)

4. 4-aminobutyrate aminotransferase, GABA-aminotransferase [53424] (2 species)

   1. Species Escherichia coli [TaxId:562] [110686] (5 PDB entries)
      Uniprot P22256

   2. Species Pig (Sus scrofa) [TaxId:9823] [53425] (3 PDB entries)

5. 5-aminolevulinate synthase [142676] (1 species)

   • Species Rhodobacter capsulatus [TaxId:1061] [142677] (1 PDB entry)
     Uniprot P18079 2-397

6. Acetylornithine/acetyl-lysine aminotransferase ArgD [142674] (1 species)

   • Species Thermus thermophilus [TaxId:274] [142675] (3 PDB entries)
     Uniprot Q93R93 9-395

7. Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, BioA [53438] (2 species)
   synonym: 7,8-diaminopelargonic acid synthase

   1. Species Bacillus subtilis [TaxId:1423] [188929] (2 PDB entries)

   2. Species Escherichia coli [TaxId:562] [53439] (11 PDB entries)

8. Aminotransferase ArnB [82488] (1 species)
   4-amino-4-deoxy-L-arabinose liposaccharide modifying enzyme

   • Species Salmonella typhimurium [TaxId:90371] [82489] (3 PDB entries)

9. Aminotransferase homolog WlaK (PglE, Cj1121c) [102603] (1 species)

   • Species Campylobacter jejuni [TaxId:197] [102604] (3 PDB entries)

10. Dialkylglycine decarboxylase [53418] (1 species)

    • Species Pseudomonas cepacia [TaxId:292] [53419] (13 PDB entries)

11. Glutamate-1-semialdehyde aminomutase (aminotransferase) [53420] (2 species)

    1. Species Synechococcus elongatus [TaxId:32046] [142669] (1 PDB entry)
       Uniprot Q8DLK8 45-437

    2. Species Synechococcus sp., strain GR6 [TaxId:1131] [53421] (3 PDB entries)

12. Ornithine aminotransferase [53422] (3 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [53423] (6 PDB entries)

    2. Species Plasmodium falciparum [TaxId:5836] [189413] (1 PDB entry)

    3. Species Plasmodium yoelii yoelii [TaxId:73239] [142670] (1 PDB entry)
       Uniprot Q7RT90 7-410

13. Phosphoserine aminotransferase, PSAT [53426] (3 species)

    1. Species Bacillus alcalophilus [TaxId:1445] [117697] (10 PDB entries)
       Uniprot Q9RME2

    2. Species Bacillus circulans, subsp. alkalophilus [TaxId:1397] [53427] (3 PDB entries)
       Uniprot Q59196

    3. Species Escherichia coli [TaxId:562] [53428] (2 PDB entries)

14. PLP-dependent acyl-CoA synthase (8-amino-7-oxonanoate synthase, AONS) [53436] (1 species)

    • Species Escherichia coli [TaxId:562] [53437] (3 PDB entries)

15. Serine hydroxymethyltransferase [53429] (6 species)

    1. Species Bacillus stearothermophilus [TaxId:1422] [75272] (39 PDB entries)

    2. Species Escherichia coli [TaxId:562] [53433] (2 PDB entries)

    3. Species Human (Homo sapiens) [TaxId:9606] [53432] (1 PDB entry)

    4. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [142671] (1 PDB entry)
       Uniprot P34897 42-504

    5. Species Mouse (Mus musculus) [TaxId:10090] [53431] (1 PDB entry)

    6. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53430] (6 PDB entries)
       Uniprot P07511

16. Spore coat polysaccharide biosynthesis protein C [142672] (1 species)

    • Species Helicobacter pylori [TaxId:210] [142673] (3 PDB entries)
      Uniprot O25130 2-372

17. automated matches [190152] (10 species)
    not a true protein

    1. Species Bacillus anthracis [TaxId:261594] [189189] (1 PDB entry)

    2. Species Bacillus subtilis [TaxId:1423] [188688] (1 PDB entry)

    3. Species Burkholderia cepacia [TaxId:292] [186906] (3 PDB entries)

    4. Species Escherichia coli [TaxId:562] [187107] (1 PDB entry)

    5. Species Rhodobacter capsulatus [TaxId:1061] [187497] (3 PDB entries)

    6. Species Salmonella typhimurium [TaxId:90371] [188804] (1 PDB entry)

    7. Species Staphylococcus aureus [TaxId:93062] [189536] (1 PDB entry)

    8. Species Synechococcus elongatus [TaxId:269084] [187818] (7 PDB entries)

    9. Species Thermus thermophilus [TaxId:300852] [187623] (1 PDB entry)

    10. Species Yersinia pestis [TaxId:214092] [189635] (1 PDB entry)

More info for Family c.67.1.4: GABA-aminotransferase-like

Timeline for Family c.67.1.4: GABA-aminotransferase-like:

• Family c.67.1.4: GABA-aminotransferase-like first appeared (with stable ids) in SCOP 1.55, called Family c.67.1.4: omega-Amino acid:pyruvate aminotransferase-like
  
• Family c.67.1.4: GABA-aminotransferase-like appears in SCOP 1.75
  
• Family c.67.1.4: GABA-aminotransferase-like appears in SCOPe 2.02
  
• Family c.67.1.4: GABA-aminotransferase-like appears in the current release, SCOPe 2.08