SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.67.1.4: GABA-aminotransferase-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2130990Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
    main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest
  4. 2130991Superfamily c.67.1: PLP-dependent transferases [53383] (10 families) (S)
  5. 2131690Family c.67.1.4: GABA-aminotransferase-like [53417] (17 protein domains)
    formerly omega-Aminoacid:pyruvate aminotransferase-like

Protein Domains:

  1. 21316911-aminocyclopropane-1-carboxylate synthase (ACC synthase) [53440] (2 species)
    1. 2131692Species Apple (Malus domestica) [TaxId:3750] [53441] (5 PDB entries)
    2. 2131699Species Tomato (Lycopersicon esculentum) [TaxId:4081] [64130] (2 PDB entries)
  2. 21317032-amino-3-ketobutyrate CoA ligase [64128] (1 species)
  3. 21317073-amino-5-hydroxybenzoic acid synthase (AHBA synthase) [53434] (1 species)
  4. 21317114-aminobutyrate aminotransferase, GABA-aminotransferase [53424] (2 species)
    1. 2131712Species Escherichia coli [TaxId:562] [110686] (5 PDB entries)
      Uniprot P22256
    2. 2131733Species Pig (Sus scrofa) [TaxId:9823] [53425] (8 PDB entries)
  5. 21317625-aminolevulinate synthase [142676] (1 species)
  6. 2131765Acetylornithine/acetyl-lysine aminotransferase ArgD [142674] (1 species)
  7. 2131773Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, BioA [53438] (2 species)
    synonym: 7,8-diaminopelargonic acid synthase
    1. 2131774Species Bacillus subtilis [TaxId:1423] [188929] (2 PDB entries)
    2. 2131779Species Escherichia coli [TaxId:562] [53439] (11 PDB entries)
  8. 2131802Aminotransferase ArnB [82488] (1 species)
    4-amino-4-deoxy-L-arabinose liposaccharide modifying enzyme
  9. 2131807Aminotransferase homolog WlaK (PglE, Cj1121c) [102603] (1 species)
  10. 2131815Dialkylglycine decarboxylase [53418] (1 species)
  11. 2131830Glutamate-1-semialdehyde aminomutase (aminotransferase) [53420] (2 species)
    1. 2131831Species Synechococcus elongatus [TaxId:32046] [142669] (1 PDB entry)
      Uniprot Q8DLK8 45-437
    2. 2131833Species Synechococcus sp., strain GR6 [TaxId:1131] [53421] (3 PDB entries)
  12. 2131840Ornithine aminotransferase [53422] (3 species)
    1. 2131841Species Human (Homo sapiens) [TaxId:9606] [53423] (6 PDB entries)
    2. 2131858Species Plasmodium falciparum [TaxId:5836] [189413] (1 PDB entry)
    3. 2131863Species Plasmodium yoelii yoelii [TaxId:73239] [142670] (1 PDB entry)
      Uniprot Q7RT90 7-410
  13. 2131870Phosphoserine aminotransferase, PSAT [53426] (3 species)
    1. 2131871Species Bacillus alcalophilus [TaxId:1445] [117697] (12 PDB entries)
      Uniprot Q9RME2
    2. 2131896Species Bacillus circulans, subsp. alkalophilus [TaxId:1397] [53427] (3 PDB entries)
      Uniprot Q59196
    3. 2131901Species Escherichia coli [TaxId:562] [53428] (2 PDB entries)
  14. 2131906PLP-dependent acyl-CoA synthase (8-amino-7-oxonanoate synthase, AONS) [53436] (1 species)
  15. 2131911Serine hydroxymethyltransferase [53429] (6 species)
    1. 2131912Species Bacillus stearothermophilus [TaxId:1422] [75272] (39 PDB entries)
    2. 2131954Species Escherichia coli [TaxId:562] [53433] (2 PDB entries)
    3. 2131963Species Human (Homo sapiens) [TaxId:9606] [53432] (1 PDB entry)
    4. 2131965Species Human (Homo sapiens), mitochondrial [TaxId:9606] [142671] (3 PDB entries)
      Uniprot P34897 42-504
    5. 2131970Species Mouse (Mus musculus) [TaxId:10090] [53431] (1 PDB entry)
    6. 2131975Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53430] (6 PDB entries)
      Uniprot P07511
  16. 2131990Spore coat polysaccharide biosynthesis protein C [142672] (1 species)
  17. 2131998automated matches [190152] (22 species)
    not a true protein
    1. 2131999Species Bacillus anthracis [TaxId:261594] [189189] (1 PDB entry)
    2. 2132004Species Bacillus subtilis [TaxId:1423] [188688] (1 PDB entry)
    3. 2132006Species Burkholderia cenocepacia [TaxId:216591] [229698] (4 PDB entries)
    4. 2132021Species Burkholderia cepacia [TaxId:292] [186906] (3 PDB entries)
    5. 2132025Species Campylobacter jejuni [TaxId:197] [275525] (1 PDB entry)
    6. 2132027Species Coxiella burnetii [TaxId:227377] [193632] (1 PDB entry)
    7. 2132030Species Escherichia coli [TaxId:562] [187107] (1 PDB entry)
    8. 2132032Species Human (Homo sapiens) [TaxId:9606] [255069] (1 PDB entry)
    9. 2132035Species Plasmodium falciparum [TaxId:36329] [255985] (1 PDB entry)
    10. 2132040Species Rhodobacter capsulatus [TaxId:1061] [187497] (3 PDB entries)
    11. 2132052Species Salmonella enterica [TaxId:90371] [237706] (1 PDB entry)
    12. 2132054Species Salmonella typhimurium [TaxId:90371] [188804] (1 PDB entry)
    13. 2132057Species Staphylococcus aureus [TaxId:93062] [189536] (1 PDB entry)
    14. 2132062Species Streptococcus thermophilus [TaxId:299768] [270038] (3 PDB entries)
    15. 2132071Species Synechococcus elongatus [TaxId:1140] [193337] (1 PDB entry)
    16. 2132073Species Synechococcus elongatus [TaxId:269084] [187818] (8 PDB entries)
    17. 2132089Species Thermus thermophilus HB8 [TaxId:300852] [187623] (1 PDB entry)
    18. 2132092Species Wild boar (Sus scrofa) [311140] (1 PDB entry)
    19. 2132097Species Yersinia pestis [TaxId:214092] [189635] (1 PDB entry)
    20. 2275153Species Arabidopsis thaliana [TaxId:3702] [318454] (1 PDB entry)
    21. 2285741Species Citrobacter rodentium [TaxId:97825] [329042] (1 PDB entry)
    22. 2291057Species Acinetobacter baumannii [TaxId:470] [334358] (1 PDB entry)

More info for Family c.67.1.4: GABA-aminotransferase-like

Timeline for Family c.67.1.4: GABA-aminotransferase-like: