SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.67.1.1: AAT-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2130990Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
    main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest
  4. 2130991Superfamily c.67.1: PLP-dependent transferases [53383] (10 families) (S)
  5. 2130992Family c.67.1.1: AAT-like [53384] (17 protein domains)

Protein Domains:

  1. 2130993AAT homologue TM1698 [142661] (1 species)
  2. 2131001Alliinase [82482] (1 species)
    cysteine sulphoxide lyase
  3. 2131005Aromatic aminoacid aminotransferase, AroAT [53392] (4 species)
    1. 2131006Species Escherichia coli K-12 [TaxId:83333] [188771] (1 PDB entry)
    2. 2131013Species Escherichia coli [TaxId:562] [53394] (1 PDB entry)
    3. 2131020Species Paracoccus denitrificans [TaxId:266] [53393] (12 PDB entries)
    4. 2131045Species Pyrococcus horikoshii [TaxId:53953] [64120] (3 PDB entries)
  4. 2131052Aspartate aminotransferase, AAT [53385] (8 species)
    1. 2131053Species Baker's yeast (Saccharomyces cerevisiae), cytosolic form [TaxId:4932] [53389] (1 PDB entry)
    2. 2131058Species Chicken (Gallus gallus), cytosolic form [TaxId:9031] [53387] (2 PDB entries)
    3. 2131063Species Chicken (Gallus gallus), mitochondria [TaxId:9031] [53386] (15 PDB entries)
    4. 2131087Species Escherichia coli [TaxId:562] [53390] (82 PDB entries)
      Uniprot P00509
    5. 2131190Species Phormidium lapideum [TaxId:32060] [82481] (1 PDB entry)
    6. 2131193Species Pig (Sus scrofa), cytosolic form [TaxId:9823] [53388] (2 PDB entries)
    7. 2131198Species Thermotoga maritima [TaxId:2336] [89754] (1 PDB entry)
      TM1255
    8. 2131201Species Thermus thermophilus [TaxId:274] [53391] (9 PDB entries)
  5. 2131232Glutamine aminotransferase [110677] (1 species)
  6. 2131239Histidinol-phosphate aminotransferase HisC [64121] (2 species)
    1. 2131240Species Escherichia coli [TaxId:562] [64122] (6 PDB entries)
    2. 2131247Species Thermotoga maritima [TaxId:2336] [102594] (5 PDB entries)
      Uniprot Q9X0D0
      TM1040
  7. 2131266Hypothetical aminotransferase PH0207 [142657] (1 species)
  8. 2131269Kynurenine--oxoglutarate transaminase I [110681] (2 species)
    1. 2131270Species Human (Homo sapiens) [TaxId:9606] [110682] (3 PDB entries)
      Uniprot Q16773
    2. 2131274Species Yellow fever mosquito (Aedes aegypti) [TaxId:7159] [142654] (3 PDB entries)
      Uniprot Q95VY4 61-477
  9. 2131280L-threonine-O-3-phosphate decarboxylase CobD [69563] (1 species)
  10. 2131287Low-specificity threonine aldolase [64123] (2 species)
    1. 2131288Species Leishmania major [TaxId:5664] [110676] (1 PDB entry)
      Uniprot O15839
    2. 2131291Species Thermotoga maritima [TaxId:2336] [64124] (5 PDB entries)
  11. 2131312Multiple substrate aminotransferase, MSAT [142655] (1 species)
  12. 2131315Phenylserine aldolase PSALD [142659] (1 species)
    most similar to the low-specificity threonine aldolase
  13. 2131318Putative alanine aminotransferase [117693] (1 species)
  14. 2131324Putative aminotransferase TM1131 [117691] (1 species)
  15. 2131328Putative methionine aminotransferase YdbL [110679] (1 species)
  16. 2131332Tyrosine aminotransferase (TAT) [53395] (1 species)
  17. 2131336automated matches [190317] (5 species)
    not a true protein
    1. 2131337Species Escherichia coli K-12 [TaxId:83333] [196886] (8 PDB entries)
    2. 2131354Species Garlic (Allium sativum) [TaxId:4682] [187134] (2 PDB entries)
    3. 2131360Species Human (Homo sapiens) [TaxId:9606] [188901] (8 PDB entries)
    4. 2131376Species Mouse (Mus musculus) [TaxId:10090] [189353] (3 PDB entries)
    5. 2287144Species Sus scrofa [TaxId:9823] [330445] (4 PDB entries)

More info for Family c.67.1.1: AAT-like

Timeline for Family c.67.1.1: AAT-like: