SCOPe 2.07: Family c.66.1.1: COMT-like

Lineage for Family c.66.1.1: COMT-like

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.1: COMT-like [53336] (4 proteins)

Proteins:

1. Caffeoyl-CoA O-methyltransferase [142573] (1 species)

   • Species Alfalfa (Medicago sativa) [TaxId:3879] [142574] (2 PDB entries)
     Uniprot Q40313 21-247

2. Catechol O-methyltransferase, COMT [53337] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [267759] (12 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [53338] (87 PDB entries)

3. COMT domain-containing protein 1, COMTD1 [142571] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142572] (1 PDB entry)
     Uniprot Q86VU5 44-262

4. automated matches [190251] (6 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [188458] (1 PDB entry)

   2. Species Mesembryanthemum crystallinum [TaxId:3544] [188404] (1 PDB entry)

   3. Species Mouse (Mus musculus) [TaxId:10090] [257424] (2 PDB entries)

   4. Species Nannospalax galili [TaxId:1026970] [357296] (6 PDB entries)

   5. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187033] (8 PDB entries)

   6. Species Sorghum (Sorghum bicolor) [TaxId:4558] [321178] (1 PDB entry)

More info for Family c.66.1.1: COMT-like

Timeline for Family c.66.1.1: COMT-like:

• Family c.66.1.1: COMT-like first appeared (with stable ids) in SCOP 1.55, called Family c.66.1.1: Catechol O-methyltransferase, COMT
  
• Family c.66.1.1: COMT-like appears in SCOPe 2.06
  
• Family c.66.1.1: COMT-like appears in the current release, SCOPe 2.08