Lineage for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 318334Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 318335Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (30 families) (S)

Families:

  1. 318336c.66.1.1: Catechol O-methyltransferase, COMT [53336] (1 protein)
  2. 318342c.66.1.2: RNA methyltransferase FtsJ [53339] (1 protein)
  3. 318347c.66.1.3: Fibrillarin homologue [53342] (1 protein)
  4. 318353c.66.1.4: Hypothetical protein MJ0882 [53345] (1 protein)
  5. 318357c.66.1.5: Glycine N-methyltransferase [53348] (1 protein)
  6. 318384c.66.1.6: Arginine methyltransferase [53351] (2 proteins)
    lacks the last two strands of the common fold replaced with a beta-sandwich oligomerisation subdomain
  7. 318398c.66.1.7: Protein-L-isoaspartyl O-methyltransferase [53354] (1 protein)
    topological variant; strand order 3214567; strand 6 is antiparallel to the rest
  8. 318412c.66.1.8: Chemotaxis receptor methyltransferase CheR, C-terminal domain [53357] (1 protein)
    contains additional N-terminal all-alpha domain, res. 11-91
  9. 318417c.66.1.11: Type II DNA methylase [53377] (3 proteins)
    circularly permuted version of the common fold
  10. 318432c.66.1.12: Plant O-methyltransferase, C-terminal domain [64111] (3 proteins)
  11. 318449c.66.1.13: Probable methyltransferase Rv2118c [64117] (1 protein)
    contains additional N-terminal beta-sandwich domain, res. 1-67
  12. 318453c.66.1.14: Hypothetical protein HI0319 (YecO) [69544] (1 protein)
  13. 318458c.66.1.15: Phenylethanolamine N-methyltransferase, PNMTase [69547] (1 protein)
  14. 318463c.66.1.16: Guanidinoacetate methyltransferase [69550] (1 protein)
  15. 318474c.66.1.17: Spermidine synthase [69557] (2 proteins)
    contains additional N-terminal tetramerisation all-beta domain, res. 1-71
  16. 318494c.66.1.18: Mycolic acid cyclopropane synthase [69560] (2 proteins)
  17. 318512c.66.1.19: Histamine methyltransferase [75261] (1 protein)
  18. 318519c.66.1.20: Glucose-inhibited division protein B (GidB) [75264] (1 protein)
  19. 318523c.66.1.21: Hypothetical Protein Yjhp [82469] (1 protein)
  20. 318529c.66.1.22: Precorrin-6Y methyltransferase (CbiT) [82472] (1 protein)
  21. 318562c.66.1.23: MraW-like putative methyltransferases [82475] (1 protein)
  22. 318569c.66.1.24: rRNA adenine dimethylase-like [88784] (2 proteins)
  23. 318583c.66.1.25: mRNA cap methylase [88785] (2 proteins)
  24. 318606c.66.1.26: C5 cytosine-specific DNA methylase, DCM [88786] (3 proteins)
  25. 318629c.66.1.27: DNA methylase TaqI [88787] (1 protein)
  26. 318640c.66.1.28: N6 adenine-specific DNA methylase, DAM [88788] (1 protein)
  27. 318644c.66.1.29: rRNA methyltransferase AviRa [89738] (1 protein)
  28. 318649c.66.1.30: N5-glutamine methyltransferase, HemK [89743] (1 protein)
  29. 318655c.66.1.31: Catalytic, N-terminal domain of histone methyltransferase Dot1l [89746] (1 protein)
  30. 318659c.66.1.32: Hypothetical protein Ta1320 [89751] (1 protein)

More info for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases

Timeline for Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases: