SCOP 1.73: Protein: Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1)

Lineage for Protein: Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1)

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.62: vWA-like [53299] (1 superfamily)
core: 3 layers, a/b/a; mixed beta-sheet of 6 strands, order 321456; strand 3 is antiparallel to the rest
Superfamily c.62.1: vWA-like [53300] (5 families)
Family c.62.1.1: Integrin A (or I) domain [53301] (10 proteins)
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) [53302] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [53303] (16 PDB entries)
1. Domains for 1cqp:
  1. Domain d1cqpa_: 1cqp A: [34127]
  2. Domain d1cqpb_: 1cqp B: [34128]
    complexed with lovastatin
    complexed with 803, mg
2. Domain for 1dgq:
  - Domain d1dgqa_: 1dgq A: [34131]
3. Domains for 1lfa:
  1. Domain d1lfaa_: 1lfa A: [34122]
  2. Domain d1lfab_: 1lfa B: [34123]
    complexed with cl, mn
4. Domain for 1mjn:
  - Domain d1mjna_: 1mjn A: [79210]
    complexed with mg; mutant
5. Domains for 1mq8:
  1. Domain d1mq8b_: 1mq8 B: [79407]
    Other proteins in same PDB: d1mq8a1, d1mq8a2, d1mq8c1, d1mq8c2
  2. Domain d1mq8d_: 1mq8 D: [79410]
    Other proteins in same PDB: d1mq8a1, d1mq8a2, d1mq8c1, d1mq8c2
    complex with ICAM-1
    complexed with mg, nag; mutant
6. Domain for 1mq9:
  - Domain d1mq9a_: 1mq9 A: [79411]
    complexed with mn; mutant
7. Domain for 1mqa:
  - Domain d1mqaa_: 1mqa A: [79412]
    mutant
8. Domains for 1rd4:
  1. Domain d1rd4a_: 1rd4 A: [97304]
  2. Domain d1rd4b_: 1rd4 B: [97305]
  3. Domain d1rd4c_: 1rd4 C: [97306]
  4. Domain d1rd4d_: 1rd4 D: [97307]
    complexed with l08
9. Domains for 1xdd:
  1. Domain d1xdda_: 1xdd A: [109567]
  2. Domain d1xddb_: 1xdd B: [109568]
    complexed with aay, mg
10. Domains for 1xdg:
  1. Domain d1xdga_: 1xdg A: [109569]
  2. Domain d1xdgb_: 1xdg B: [109570]
    complexed with ab8, mg
11. Domains for 1xuo:
  1. Domain d1xuoa1: 1xuo A:128-308 [122336]
    automatically matched to d1dgqa_
    complexed with la1, mg
  2. Domain d1xuob1: 1xuo B:128-302 [122337]
    automatically matched to d1dgqa_
    complexed with la1, mg
12. Domain for 1zon:
  - Domain d1zona_: 1zon A: [34126]
    mutant
13. Domains for 1zoo:
  1. Domain d1zooa_: 1zoo A: [34129]
  2. Domain d1zoob_: 1zoo B: [34130]
    complexed with cl, mg; mutant
14. Domains for 1zop:
  1. Domain d1zopa_: 1zop A: [34124]
  2. Domain d1zopb_: 1zop B: [34125]
    complexed with cl, mn; mutant
15. Domain for 2ica:
  - Domain d2icaa1: 2ica A:129-306 [137236]
    automatically matched to d1rd4a_
    complexed with 2ic
16. Domain for 2o7n:
  - Domain d2o7na1: 2o7n A:129-306 [138929]
    automatically matched to d1rd4a_
    complexed with 2o7

More info for Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain

Timeline for Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain:

Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain first appeared (with stable ids) in SCOP 1.55
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain appears in SCOP 1.71
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain appears in SCOP 1.75
Protein Integrin CD11a/CD18 (Leukocyte function associated antigen-1, LFA-1) from c.62.1.1: Integrin A (or I) domain appears in the current release, SCOPe 2.08