SCOPe 2.06: Protein: Carboxypeptidase A

Lineage for Protein: Carboxypeptidase A

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families)
core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
Family c.56.5.1: Pancreatic carboxypeptidases [53188] (5 proteins)
Protein Carboxypeptidase A [53189] (4 species)

Species:

Cotton bollworm (Helicoverpa armigera) [TaxId:29058] [75247] (1 PDB entry)
- Domain for 1jqg:
  - Domain d1jqga1: 1jqg A:1-310 [71791]
    Other proteins in same PDB: d1jqga2
    complexed with zn
Cow (Bos taurus) [TaxId:9913] [53190] (34 PDB entries)
1. Domain for 1arl:
  - Domain d1arla_: 1arl A: [33812]
2. Domain for 1arm:
  - Domain d1arma_: 1arm A: [33810]
    complexed with cu, hg, trs
3. Domains for 1bav:
  1. Domain d1bava_: 1bav A: [33806]
    complexed with bip, zn
  2. Domain d1bavb_: 1bav B: [33807]
    complexed with bip, zn
  3. Domain d1bavc_: 1bav C: [33808]
    complexed with bip, zn
  4. Domain d1bavd_: 1bav D: [33809]
    complexed with bip, zn
4. Domain for 1cbx:
  - Domain d1cbxa_: 1cbx A: [33813]
    complexed with bzs, zn
5. Domain for 1cps:
  - Domain d1cpsa_: 1cps A: [33818]
    complexed with cpm, zn
6. Domain for 1cpx:
  - Domain d1cpxa_: 1cpx A: [33814]
    truncated beta form with two zinc ions in the active site
    complexed with oh, zn
7. Domain for 1ee3:
  - Domain d1ee3p_: 1ee3 P: [70128]
    complexed with cd
8. Domain for 1ell:
  - Domain d1ellp_: 1ell P: [70129]
    complexed with cd
9. Domain for 1elm:
  - Domain d1elmp_: 1elm P: [70130]
    complexed with cd
10. Domain for 1f57:
  - Domain d1f57a_: 1f57 A: [33805]
    complexed with dcy, zn
11. Domain for 1hdq:
  - Domain d1hdqa_: 1hdq A: [65809]
    complexed with inf, zn
12. Domains for 1hdu:
  1. Domain d1hdua_: 1hdu A: [65810]
    complexed with ing, zn
  2. Domain d1hdub_: 1hdu B: [65811]
    complexed with ing, zn
  3. Domain d1hdud_: 1hdu D: [65812]
    complexed with ing, zn
  4. Domain d1hdue_: 1hdu E: [65813]
    complexed with ing, zn
13. Domains for 1hee:
  1. Domain d1heea_: 1hee A: [65814]
    complexed with lhy, zn
  2. Domain d1heeb_: 1hee B: [65815]
    complexed with lhy, zn
  3. Domain d1heed_: 1hee D: [65816]
    complexed with lhy, zn
  4. Domain d1heee_: 1hee E: [65817]
    complexed with lhy, zn
14. Domain for 1iy7:
  - Domain d1iy7a_: 1iy7 A: [76942]
    complexed with cxa, zn
15. Domain for 1m4l:
  - Domain d1m4la_: 1m4l A: [78604]
    high resolution structure
    complexed with zn
16. Domain for 1pyt:
  - Domain d1pytb_: 1pyt B: [33820]
    Other proteins in same PDB: d1pyta_, d1pytc_, d1pytd_
    complexed with ca, zn
17. Domain for 1yme:
  - Domain d1ymea_: 1yme A: [33804]
    complexed with zn
18. Domain for 1zlh:
  - Domain d1zlha_: 1zlh A: [125251]
    Other proteins in same PDB: d1zlhb1, d1zlhb2
    automated match to d1pytb_
    complexed with zn
19. Domains for 2abz:
  1. Domain d2abza_: 2abz A: [126537]
    Other proteins in same PDB: d2abzc1, d2abzd_, d2abze_, d2abzf_
    automated match to d1pytb_
    complexed with zn; mutant
  2. Domain d2abzb_: 2abz B: [126538]
    Other proteins in same PDB: d2abzc1, d2abzd_, d2abze_, d2abzf_
    automated match to d1pytb_
    complexed with zn; mutant
20. Domain for 2ctb:
  - Domain d2ctba_: 2ctb A: [33803]
    complexed with zn
21. Domain for 2ctc:
  - Domain d2ctca_: 2ctc A: [33802]
    complexed with hfa, zn
22. Domain for 2rfh:
  - Domain d2rfha_: 2rfh A: [151995]
    automated match to d1arla_
    complexed with 23n, zn
23. Domain for 3cpa:
  - Domain d3cpaa_: 3cpa A: [33819]
    complexed with gly, tyr, zn
24. Domains for 3fvl:
  1. Domain d3fvla_: 3fvl A: [176081]
    automated match to d1arla_
    complexed with bhk, zn
  2. Domain d3fvlc_: 3fvl C: [176082]
    automated match to d1arla_
    complexed with bhk, zn
  3. Domain d3fvle_: 3fvl E: [176083]
    automated match to d1arla_
    complexed with bhk, zn
25. Domains for 3fx6:
  1. Domain d3fx6a_: 3fx6 A: [176125]
    automated match to d1arla_
    complexed with bpx, zn
  2. Domain d3fx6c_: 3fx6 C: [176126]
    automated match to d1arla_
    complexed with bpx, zn
  3. Domain d3fx6e_: 3fx6 E: [176127]
    automated match to d1arla_
    complexed with bpx, zn
26. Domains for 3hlp:
  1. Domain d3hlpa_: 3hlp A: [177678]
    automated match to d1pytb_
    complexed with mpd, mrd, zn
  2. Domain d3hlpb_: 3hlp B: [177679]
    automated match to d1pytb_
    complexed with mpd, mrd, zn
27. Domain for 3huv:
  - Domain d3huva_: 3huv A: [177853]
    automated match to d1pytb_
    complexed with zn
28. Domain for 3i1u:
  - Domain d3i1ua_: 3i1u A: [178022]
    automated match to d1pytb_
    complexed with btw, gol, zn
29. Domain for 3kgq:
  - Domain d3kgqa_: 3kgq A: [179357]
    automated match to d1pytb_
    complexed with acn, cit, fmt, gol, na, zn
30. Domains for 4cpa:
  1. Domain d4cpaa_: 4cpa A: [33821]
    Other proteins in same PDB: d4cpai_, d4cpaj_
    complexed with gly, zn
  2. Domain d4cpab_: 4cpa B: [118682]
    Other proteins in same PDB: d4cpai_, d4cpaj_
    duplicate of 4CPA
    complexed with gly, zn
31. Domain for 5cpa:
  - Domain d5cpaa_: 5cpa A: [33811]
    complexed with zn
32. Domain for 6cpa:
  - Domain d6cpaa_: 6cpa A: [33816]
    complexed with zaf, zn
33. Domain for 7cpa:
  - Domain d7cpaa_: 7cpa A: [33815]
    complexed with fvf, zn
34. Domain for 8cpa:
  - Domain d8cpaa_: 8cpa A: [33817]
    complexed with agf, zn
Human (Homo sapiens) [TaxId:9606] [53192] (6 PDB entries)
1. Domain for 1aye:
  - Domain d1ayea1: 1aye A:1-309 [33824]
    Other proteins in same PDB: d1ayea2
    procarboxypeptidase A2
    complexed with zn
2. Domain for 1dtd:
  - Domain d1dtda_: 1dtd A: [33823]
    Other proteins in same PDB: d1dtdb_
    complexed with glu, zn
3. Domains for 2bk7:
  1. Domain d2bk7a_: 2bk7 A: [303587]
    Other proteins in same PDB: d2bk7b1, d2bk7b2, d2bk7d1, d2bk7d2
    automated match to d2bo9a1
    complexed with acn, mpd, nag, val, zn
  2. Domain d2bk7c_: 2bk7 C: [303590]
    Other proteins in same PDB: d2bk7b1, d2bk7b2, d2bk7d1, d2bk7d2
    automated match to d2bo9a1
    complexed with acn, mpd, nag, val, zn
4. Domains for 2bo9:
  1. Domain d2bo9a1: 2bo9 A:4-307 [128897]
    Other proteins in same PDB: d2bo9b1, d2bo9b2, d2bo9d1, d2bo9d2
    Procarboxypeptidase A4
    complexed with acn, mpd, nag, val, zn
  2. Domain d2bo9c_: 2bo9 C: [128900]
    Other proteins in same PDB: d2bo9b1, d2bo9b2, d2bo9d1, d2bo9d2
    automated match to d2bo9a1
    complexed with acn, mpd, nag, val, zn
5. Domains for 2boa:
  1. Domain d2boaa1: 2boa A:1001-1309 [128903]
    Other proteins in same PDB: d2boaa2, d2boab2
    Procarboxypeptidase A4
    complexed with gol, nag, zn
  2. Domain d2boab1: 2boa B:1001-1309 [128905]
    Other proteins in same PDB: d2boaa2, d2boab2
    automated match to d2boaa1
    complexed with gol, nag, zn
6. Domain for 2pcu:
  - Domain d2pcua1: 2pcu A:5-307 [139655]
    automatically matched to 2BO9 A:4-307
    complexed with asp, gol, nag, scn, zn
Pig (Sus scrofa) [TaxId:9823] [53191] (1 PDB entry)
- Domain for 1pca:
  - Domain d1pcaa2: 1pca A:1-308 [33822]
    Other proteins in same PDB: d1pcaa1
    zymogen
    complexed with cit, val, zn

More info for Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases

Timeline for Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases:

Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases first appeared (with stable ids) in SCOP 1.55
Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases appears in SCOPe 2.05
Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases appears in SCOPe 2.07
Protein Carboxypeptidase A from c.56.5.1: Pancreatic carboxypeptidases appears in the current release, SCOPe 2.08