Lineage for Family c.56.2.1: Purine and uridine phosphorylases

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2125386Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2125403Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families) (S)
    complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8
  5. 2125404Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 protein domains)

Protein Domains:

  1. 21254055'-deoxy-5'-methylthioadenosine phosphorylase [53174] (3 species)
    1. 2125406Species Human (Homo sapiens) [TaxId:9606] [53175] (9 PDB entries)
      Uniprot Q13126
    2. 2125421Species Sulfolobus solfataricus [TaxId:2287] [69536] (9 PDB entries)
    3. 2125458Species Sulfolobus tokodaii [TaxId:111955] [117657] (1 PDB entry)
      Uniprot Q975C3
  2. 21254625'-Methylthioadenosine/S-Adenosylhomocysteine nucleosidase [82448] (3 species)
    1. 2125463Species Escherichia coli [TaxId:562] [82449] (8 PDB entries)
    2. 2125479Species Neisseria meningitidis [TaxId:491] [188964] (1 PDB entry)
    3. 2125482Species Staphylococcus aureus [TaxId:1280] [188463] (1 PDB entry)
  3. 2125484AMP nucleosidase [110645] (2 species)
    contains extra N-terminal oligomerisation (sub)domain (8-153)
    1. 2125485Species Bacteroides thetaiotaomicron [TaxId:818] [117658] (1 PDB entry)
      Uniprot Q7MVU1
    2. 2125489Species Escherichia coli [TaxId:562] [110646] (4 PDB entries)
      Uniprot P15272
  4. 2125514Purine nucleoside phosphorylase, PNP [53169] (13 species)
    1. 2125515Species Anthrax bacillus (Bacillus anthracis) [TaxId:1392] [117655] (1 PDB entry)
      Uniprot Q81T09
    2. 2125522Species Bacillus cereus [TaxId:1396] [195935] (5 PDB entries)
    3. 2125528Species Bacillus cereus [TaxId:269801] [186942] (1 PDB entry)
    4. 2125531Species Cellulomonas sp. [TaxId:40001] [53173] (2 PDB entries)
    5. 2125538Species Cow (Bos taurus) [TaxId:9913] [53171] (20 PDB entries)
      Uniprot P55859
    6. 2125571Species Escherichia coli [TaxId:562] [53172] (28 PDB entries)
    7. 2125692Species Human (Homo sapiens) [TaxId:9606] [53170] (29 PDB entries)
      Uniprot P00491
    8. 2125731Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [226822] (1 PDB entry)
    9. 2125738Species Mycobacterium tuberculosis [TaxId:1773] [64098] (3 PDB entries)
    10. 2125748Species Thermotoga maritima [TaxId:2336] [117654] (1 PDB entry)
      Uniprot Q9X1T2
    11. 2125752Species Thermus thermophilus [TaxId:274] [89721] (4 PDB entries)
    12. 2125777Species Vibrio cholerae [TaxId:666] [102499] (2 PDB entries)
    13. 2286683Species Escherichia coli [TaxId:331111] [329984] (1 PDB entry)
  5. 2125790Putative uridine phosphorylase [102500] (1 species)
  6. 2125805Uridine phosphorylase [53176] (6 species)
    1. 2125806Species Escherichia coli [TaxId:562] [53177] (16 PDB entries)
    2. 2125909Species Salmonella enterica [TaxId:54388] [311321] (1 PDB entry)
    3. 2125919Species Salmonella typhimurium [TaxId:90371] [117656] (24 PDB entries)
      Uniprot P0A1F6
    4. 2126047Species Vibrio cholerae [TaxId:243277] [224899] (13 PDB entries)
    5. 2126096Species Yersinia pestis [TaxId:632] [238361] (1 PDB entry)
    6. 2126103Species Yersinia pseudotuberculosis [TaxId:633] [229814] (2 PDB entries)
  7. 2126112automated matches [190142] (19 species)
    not a true protein
    1. 2126113Species Aeropyrum pernix [TaxId:272557] [188092] (1 PDB entry)
    2. 2126115Species Bacillus subtilis [TaxId:1423] [193503] (14 PDB entries)
    3. 2126140Species Cow (Bos taurus) [TaxId:9913] [187265] (1 PDB entry)
    4. 2126142Species Escherichia coli [TaxId:562] [186867] (5 PDB entries)
    5. 2126162Species Human (Homo sapiens) [TaxId:9606] [256021] (7 PDB entries)
    6. 2126187Species Klebsiella pneumoniae [TaxId:272620] [193517] (1 PDB entry)
    7. 2126190Species Malaria parasite (Plasmodium knowlesi) [TaxId:5850] [225033] (1 PDB entry)
    8. 2126192Species Mycobacterium tuberculosis [TaxId:1773] [189596] (2 PDB entries)
    9. 2126197Species Plasmodium falciparum [TaxId:36329] [186993] (3 PDB entries)
    10. 2126207Species Plasmodium vivax [TaxId:5855] [188970] (1 PDB entry)
    11. 2126209Species Salmonella enterica [TaxId:904139] [196952] (5 PDB entries)
    12. 2126220Species Salmonella typhimurium [TaxId:99287] [187772] (1 PDB entry)
    13. 2126224Species Sulfolobus solfataricus [TaxId:2287] [187383] (2 PDB entries)
    14. 2126243Species Trichomonas vaginalis [TaxId:5722] [187838] (9 PDB entries)
    15. 2126260Species Vibrio cholerae [TaxId:243277] [189490] (2 PDB entries)
    16. 2126275Species Vibrio cholerae [TaxId:666] [188799] (2 PDB entries)
    17. 2126290Species Yersinia pseudotuberculosis [TaxId:273123] [268417] (1 PDB entry)
    18. 2126293Species Yersinia pseudotuberculosis [TaxId:502800] [189524] (1 PDB entry)
    19. 2285470Species Vibrio fischeri [TaxId:312309] [328771] (1 PDB entry)

More info for Family c.56.2.1: Purine and uridine phosphorylases

Timeline for Family c.56.2.1: Purine and uridine phosphorylases: