Lineage for Protein: Mammalian type I hexokinase

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 586264Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 586265Superfamily c.55.1: Actin-like ATPase domain [53067] (11 families) (S)
    duplication contains two domains of this fold
  5. 586454Family c.55.1.3: Hexokinase [53083] (3 proteins)
  6. 586468Protein Mammalian type I hexokinase [53086] (2 species)
    further duplication: consists of two very similar lobes

Species:

  1. 586469Human (Homo sapiens) [TaxId:9606] [53087] (5 PDB entries)
    1. Domains for 1cza:
      1. 586470Domain d1czan1: 1cza N:16-222 [33463]
      2. 586471Domain d1czan2: 1cza N:223-465 [33464]
      3. 586472Domain d1czan3: 1cza N:466-670 [33465]
      4. 586473Domain d1czan4: 1cza N:671-913 [33466]
        complexed with adp, g6p, glc; mutant
    2. Domains for 1dgk:
      1. 586494Domain d1dgkn1: 1dgk N:16-222 [33487]
      2. 586495Domain d1dgkn2: 1dgk N:223-465 [33488]
      3. 586496Domain d1dgkn3: 1dgk N:466-670 [33489]
      4. 586497Domain d1dgkn4: 1dgk N:671-913 [33490]
        complexed with adp, glc, po4; mutant
    3. Domains for 1hkb:
      1. 586486Domain d1hkba1: 1hkb A:16-222 [33479]
      2. 586487Domain d1hkba2: 1hkb A:223-465 [33480]
      3. 586488Domain d1hkba3: 1hkb A:466-670 [33481]
      4. 586489Domain d1hkba4: 1hkb A:671-914 [33482]
      5. 586490Domain d1hkbb1: 1hkb B:16-222 [33483]
      6. 586491Domain d1hkbb2: 1hkb B:223-465 [33484]
      7. 586492Domain d1hkbb3: 1hkb B:466-670 [33485]
      8. 586493Domain d1hkbb4: 1hkb B:671-914 [33486]
        complexed with ca, g6p, glc
    4. Domains for 1hkc:
      1. 586482Domain d1hkca1: 1hkc A:16-222 [33475]
      2. 586483Domain d1hkca2: 1hkc A:223-465 [33476]
      3. 586484Domain d1hkca3: 1hkc A:466-670 [33477]
      4. 586485Domain d1hkca4: 1hkc A:671-914 [33478]
        complexed with glc, k, po4
    5. Domains for 1qha:
      1. 586474Domain d1qhaa1: 1qha A:12-222 [33467]
      2. 586475Domain d1qhaa2: 1qha A:223-465 [33468]
      3. 586476Domain d1qhaa3: 1qha A:466-670 [33469]
      4. 586477Domain d1qhaa4: 1qha A:671-914 [33470]
      5. 586478Domain d1qhab1: 1qha B:16-222 [33471]
      6. 586479Domain d1qhab2: 1qha B:223-465 [33472]
      7. 586480Domain d1qhab3: 1qha B:466-670 [33473]
      8. 586481Domain d1qhab4: 1qha B:671-914 [33474]
  2. 586498Rat (Rattus norvegicus) [TaxId:10116] [53088] (1 PDB entry)

More info for Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase

Timeline for Protein Mammalian type I hexokinase from c.55.1.3: Hexokinase: