SCOPe 2.01: Family c.55.1.1: Actin/HSP70

Lineage for Family c.55.1.1: Actin/HSP70

1. Root: SCOPe 2.01

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.1: Actin-like ATPase domain [53067] (14 families)
   duplication contains two domains of this fold

5. Family c.55.1.1: Actin/HSP70 [53068] (7 proteins)

Proteins:

1. Actin [53073] (6 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [53077] (2 PDB entries)

   2. Species Chicken (Gallus gallus) [TaxId:9031] [82437] (1 PDB entry)
      sequence identical to the rabbit actin

   3. Species Cow (Bos taurus) [TaxId:9913] [53074] (26 PDB entries)

   4. Species Nematode (Caenorhabditis elegans) [TaxId:6239] [64086] (1 PDB entry)

   5. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53075] (20 PDB entries)
      Uniprot P02568 ! SQ 02568

   6. Species Slime mold (Dictyostelium discoideum) [TaxId:44689] [53076] (6 PDB entries)

2. Actin-related protein 2, Arp2 [69530] (1 species)
   part of Arp2/3 complex

   • Species Cow (Bos taurus) [TaxId:9913] [69531] (3 PDB entries)
     Uniprot P61160 143-350 # 100% sequence identity

3. Actin-related protein 3, Arp3 [69528] (1 species)
   part of Arp2/3 complex

   • Species Cow (Bos taurus) [TaxId:9913] [69529] (10 PDB entries)
     Uniprot P61158

4. Cell division protein FtsA [53078] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [53079] (2 PDB entries)

5. Heat shock protein 70kDa, ATPase fragment [53069] (3 species)

   1. Species Cow (Bos taurus) [TaxId:9913] [53070] (35 PDB entries)

   2. Species Escherichia coli, gene dnaK [TaxId:562] [53072] (1 PDB entry)

   3. Species Human (Homo sapiens) [TaxId:9606] [53071] (6 PDB entries)

6. Plasmid segregation protein ParM [82438] (1 species)

   • Species Escherichia coli [TaxId:562] [82439] (6 PDB entries)

7. Prokaryotic actin homolog MreB [64087] (1 species)

   • Species Thermotoga maritima [TaxId:2336] [64088] (3 PDB entries)

More info for Family c.55.1.1: Actin/HSP70

Timeline for Family c.55.1.1: Actin/HSP70:

• Family c.55.1.1: Actin/HSP70 first appeared (with stable ids) in SCOP 1.55
  
• Family c.55.1.1: Actin/HSP70 appears in SCOP 1.75
  
• Family c.55.1.1: Actin/HSP70 appears in SCOPe 2.02
  
• Family c.55.1.1: Actin/HSP70 appears in the current release, SCOPe 2.08