Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.120: PIN domain-like [88722] (1 superfamily) 3 layers, a/b/a; core: parallel beta-sheet of 5 strands, order 32145 |
Superfamily c.120.1: PIN domain-like [88723] (3 families) |
Family c.120.1.2: 5' to 3' exonuclease catalytic domain [53045] (4 proteins) contains an alpha-helical arch and additional strand 6 antiparallel to the rest; strand order 321456; similarity to the resolvase-like fold |
Protein Flap endonuclease-1 (Fen-1 nuclease) [53052] (5 species) |
Archaeoglobus fulgidus [TaxId:2234] [102272] (2 PDB entries) |
Domain d1rxva2: 1rxv A:4-219 [98056] Other proteins in same PDB: d1rxva1, d1rxvb1 protein/DNA complex |
Domain d1rxvb2: 1rxv B:4-219 [98058] Other proteins in same PDB: d1rxva1, d1rxvb1 protein/DNA complex |
Domain d1rxwa2: 1rxw A:3-219 [98060] Other proteins in same PDB: d1rxwa1 protein/DNA complex |
Human (Homo sapiens) [TaxId:9606] [142118] (1 PDB entry) Uniprot P39748 2-217 |
Domain d1ul1x2: 1ul1 X:2-217 [119691] Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1 protein/DNA complex; complexed with mg |
Domain d1ul1y2: 1ul1 Y:2-217 [119693] Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1 automated match to d1ul1x2 protein/DNA complex; complexed with mg |
Domain d1ul1z2: 1ul1 Z:2-217 [119695] Other proteins in same PDB: d1ul1a1, d1ul1a2, d1ul1b1, d1ul1b2, d1ul1c1, d1ul1c2, d1ul1x1, d1ul1y1, d1ul1z1 automated match to d1ul1x2 protein/DNA complex; complexed with mg |
Methanococcus jannaschii [TaxId:2190] [53053] (2 PDB entries) |
Domain d1a76a2: 1a76 A:2-208 [33361] Other proteins in same PDB: d1a76a1 complexed with mn |
Domain d1a77a2: 1a77 A:2-208 [33360] Other proteins in same PDB: d1a77a1 complexed with mg |
Pyrococcus furiosus [TaxId:2261] [53055] (1 PDB entry) |
Domain d1b43a2: 1b43 A:1-219 [33362] Other proteins in same PDB: d1b43a1, d1b43b1 |
Domain d1b43b2: 1b43 B:1-219 [33363] Other proteins in same PDB: d1b43a1, d1b43b1 |
Pyrococcus horikoshii [TaxId:53953] [82436] (1 PDB entry) |
Domain d1mc8a2: 1mc8 A:2-220 [78946] Other proteins in same PDB: d1mc8a1, d1mc8b1 mutant |
Domain d1mc8b2: 1mc8 B:2-220 [78948] Other proteins in same PDB: d1mc8a1, d1mc8b1 mutant |
Timeline for Protein Flap endonuclease-1 (Fen-1 nuclease) from c.120.1.2: 5' to 3' exonuclease catalytic domain: