SCOP 1.73: Family c.47.1.10: Glutathione peroxidase-like

Lineage for Family c.47.1.10: Glutathione peroxidase-like

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

4. Superfamily c.47.1: Thioredoxin-like [52833] (22 families)

5. Family c.47.1.10: Glutathione peroxidase-like [52901] (28 proteins)

Proteins:

1. 1-Cys peroxiredoxin [52909] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [52910] (1 PDB entry)

   2. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142367] (1 PDB entry)

   3. Species Plasmodium yoelii yoelii [TaxId:73239] [117599] (1 PDB entry)

2. Alkyl hydroperoxide reductase AhpC [69516] (3 species)

   1. Species Amphibacillus xylanus [TaxId:1449] [142369] (1 PDB entry)

   2. Species Mycobacterium tuberculosis [TaxId:1773] [142368] (1 PDB entry)

   3. Species Salmonella typhimurium [TaxId:90371] [69517] (5 PDB entries)

3. Bacterioferritin comigratory protein [142377] (1 species)

   • Species Archaeon Aeropyrum pernix [TaxId:56636] [142378] (2 PDB entries)

4. Glutathione peroxidase [52902] (2 species)
   contains many insertions in the common fold

   1. Species Cow (Bos taurus) [TaxId:9913] [52903] (1 PDB entry)

   2. Species Human (Homo sapiens) [TaxId:9606] [142365] (1 PDB entry)

5. Lipoprotein DsbF [142375] (1 species)

   • Species Mycobacterium tuberculosis [TaxId:1773] [142376] (1 PDB entry)

6. Membrane-anchored thioredoxin-like protein TlpA, soluble domain [64068] (1 species)

   • Species Bradyrhizobium japonicum [TaxId:375] [64069] (1 PDB entry)

7. N-terminal, Prx domain of Hybrid-Prx5 [89708] (1 species)

   • Species Haemophilus influenzae [TaxId:727] [89709] (1 PDB entry)
     HI0572

8. Peptide methionine sulfoxide reductase MsrA/MsrB, N-terminal domain [142385] (1 species)

   • Species Neisseria meningitidis serogroup A [TaxId:65699] [142386] (1 PDB entry)

9. Peroxiredoxin [117601] (1 species)

   • Species Aeropyrum pernix [TaxId:56636] [117602] (2 PDB entries)

10. Peroxiredoxin 5 [64066] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [64067] (4 PDB entries)

11. Peroxiredoxin dot5 [142387] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [142388] (1 PDB entry)

12. Peroxiredoxin-3 (AOP-1, SP-22) [142391] (1 species)

    • Species Cow (Bos taurus) [TaxId:9913] [142392] (1 PDB entry)

13. Phenol hydroxylase, C-terminal domain [52911] (1 species)

    • Species Soil-living yeast (Trichosporon cutaneum) [TaxId:5554] [52912] (2 PDB entries)

14. Plant peroxiredoxin [142379] (1 species)

    • Species Western balsam poplar(Populus trichocarpa) [TaxId:3694] [142380] (1 PDB entry)

15. Probable thiol peroxidase PsaD [89710] (1 species)

    • Species Streptococcus pneumoniae [TaxId:1313] [89711] (1 PDB entry)

16. Probable thiol-disulfide isomerase/thioredoxin TTHA0593 [142389] (1 species)

    • Species Thermus thermophilus [TaxId:274] [142390] (1 PDB entry)

17. Putative peroxiredoxin Rv2238c/MT2298 [142381] (1 species)

    • Species Mycobacterium tuberculosis [TaxId:1773] [142382] (2 PDB entries)

18. Soluble secreted antigen MPT53 [102457] (1 species)

    • Species Mycobacterium tuberculosis [TaxId:1773] [102458] (1 PDB entry)

19. Thiol peroxidase Tpx [102452] (3 species)

    1. Species Escherichia coli [TaxId:562] [102453] (1 PDB entry)

    2. Species Haemophilus influenzae [TaxId:727] [102454] (1 PDB entry)
       HI0751

    3. Species Mycobacterium tuberculosis [TaxId:1773] [117600] (2 PDB entries)

20. Thiol-disulfide oxidoreductase ResA [102455] (1 species)

    • Species Bacillus subtilis [TaxId:1423] [102456] (4 PDB entries)

21. thiol:disulfide oxidoreductase YkuV [142373] (1 species)

    • Species Bacillus subtilis [TaxId:1423] [142374] (2 PDB entries)

22. Thioredoxin peroxidase 2 (thioredoxin peroxidase B, 2-cys peroxiredoxin) [52906] (3 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [52908] (1 PDB entry)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [52907] (1 PDB entry)
       heme-binding protein 23, HBP23

    3. Species Plasmodium yoelii [TaxId:5861] [142366] (1 PDB entry)

23. Thioredoxin reductase TsaA [142383] (1 species)

    • Species Helicobacter pylori [TaxId:210] [142384] (1 PDB entry)

24. Thioredoxin-like protein CcmG (CycY, DsbE) [75237] (2 species)

    1. Species Bradyrhizobium japonicum [TaxId:375] [75238] (1 PDB entry)

    2. Species Escherichia coli [TaxId:562] [142370] (1 PDB entry)

25. Thioredoxin-like protein Sco1 (YpmQ), soluble domain [102459] (3 species)

    1. Species Bacillus subtilis [TaxId:1423] [102460] (2 PDB entries)

    2. Species Baker's yeast(Saccharomyces cerevisiae) [TaxId:4932] [142372] (2 PDB entries)

    3. Species Human (Homo sapiens) [TaxId:9606] [142371] (2 PDB entries)

26. Tryparedoxin I [52904] (2 species)

    1. Species Crithidia fasciculata [TaxId:5656] [52905] (8 PDB entries)

    2. Species Trypanosoma brucei brucei [TaxId:5702] [89707] (1 PDB entry)

27. Tryparedoxin II [64062] (1 species)

    • Species Crithidia fasciculata [TaxId:5656] [64063] (6 PDB entries)

28. Tryparedoxin peroxidase (thioredoxin peroxidase homologue) [64064] (2 species)

    1. Species Crithidia fasciculata [TaxId:5656] [64065] (1 PDB entry)

    2. Species Trypanosoma cruzi [TaxId:5693] [117598] (1 PDB entry)

More info for Family c.47.1.10: Glutathione peroxidase-like

Timeline for Family c.47.1.10: Glutathione peroxidase-like:

• Family c.47.1.10: Glutathione peroxidase-like first appeared (with stable ids) in SCOP 1.55
  
• Family c.47.1.10: Glutathione peroxidase-like appears in SCOP 1.71
  
• Family c.47.1.10: Glutathione peroxidase-like appears in SCOP 1.75
  
• Family c.47.1.10: Glutathione peroxidase-like appears in the current release, SCOPe 2.08