SCOP 1.63: Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain

Lineage for Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

4. Superfamily c.47.1: Thioredoxin-like [52833] (12 families)

5. Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain [52862] (15 proteins)

Proteins:

1. Chloride intracellular channel 1 (clic1) [69514] (1 species)
   similar to class theta enzymes

   • Species Human (Homo sapiens) [TaxId:9606] [69515] (3 PDB entries)

2. Class alpha GST [81360] (6 species)

   1. Species Fasciola hepatica [TaxId:6192] [52879] (2 PDB entries)

   2. Species Human (Homo sapiens), (a1-1) [TaxId:9606] [52870] (10 PDB entries)

   3. Species Mouse (Mus musculus), (a1-1) [TaxId:10090] [52872] (2 PDB entries)

   4. Species Mouse (Mus musculus), (a1-4) [TaxId:10090] [52873] (2 PDB entries)

   5. Species Rat (Rattus norvegicus), (a1-1) [TaxId:10116] [52871] (2 PDB entries)

   6. Species Schistosoma japonicum [TaxId:6182] [52878] (5 PDB entries)

3. Class beta GST [81368] (3 species)

   1. Species Escherichia coli [TaxId:562] [52883] (2 PDB entries)

   2. Species Proteus mirabilis [TaxId:584] [52884] (2 PDB entries)

   3. Species Sphingomonas paucimobilis [TaxId:13689] [52885] (1 PDB entry)

4. Class delta GST [81366] (2 species)
   formerly a part of class theta enzymes

   1. Species Insect (Anopheles dirus b), isozyme 1-3 [75234] (1 PDB entry)

   2. Species Insect (Anopheles dirus b), isozyme 1-4 [75235] (1 PDB entry)

5. Class mu GST [81359] (3 species)

   1. Species Chicken (Gallus gallus) [TaxId:9031] [52869] (2 PDB entries)

   2. Species Human (Homo sapiens) [TaxId:9606] [52867] (7 PDB entries)

   3. Species Rat (Rattus norvegicus) [TaxId:10116] [52868] (14 PDB entries)

6. Class omega GST [81363] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [52877] (1 PDB entry)

7. Class phi GST [81367] (3 species)

   1. Species Maize (Zea mays), type I [TaxId:4577] [52881] (2 PDB entries)

   2. Species Maize (Zea mays), type III [TaxId:4577] [52882] (1 PDB entry)

   3. Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [52880] (2 PDB entries)

8. Class pi GST [81358] (3 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [52864] (33 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [52866] (6 PDB entries)

   3. Species Pig (Sus scrofa) [TaxId:9823] [52865] (1 PDB entry)

9. Class sigma GST [81362] (3 species)

   1. Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [82427] (1 PDB entry)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [52875] (1 PDB entry)
      synonym: hematopoietic prostaglandin D synthase

   3. Species Squid (Ommastrephes sloani pacificus) [TaxId:6634] [52876] (2 PDB entries)

10. Class tau GST [81365] (1 species)

    • Species Wheat (Triticum tauschii l.) [75236] (1 PDB entry)

11. Class theta GST [81361] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [52874] (3 PDB entries)

12. Class zeta GST [81364] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [64058] (1 PDB entry)
       maleylacetoacetate isomerase

    2. Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [64059] (1 PDB entry)

13. Glutaredoxin 2 [64060] (1 species)
    similar to class zeta enzymes

    • Species Escherichia coli [TaxId:562] [64061] (1 PDB entry)

14. GST-like domain of elongation factor 1-gamma [82428] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82429] (1 PDB entry)

15. Yeast prion protein ure2p, nitrogen regulation fragment [52886] (1 species)
    similar to class phi enzymes

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52887] (8 PDB entries)

More info for Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain

Timeline for Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain:

• Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain first appeared (with stable ids) in SCOP 1.55, called Family c.47.1.5: Glutathione S-transferases, N-terminal domain
  
• Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain was called Family c.47.1.5: Glutathione S-transferases, N-terminal domain in SCOP 1.61
  
• Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain appears in SCOP 1.65
  
• Family c.47.1.5: Glutathione S-transferase (GST), N-terminal domain appears in the current release, SCOPe 2.08