Lineage for Protein: Tyrosine phosphatase

  1. Root: SCOPe 2.04
  2. 1565955Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1599809Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 1599810Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 1599892Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 1599932Protein Tyrosine phosphatase [52806] (7 species)

Species:

  1. 1599933Human (Homo sapiens), 1B [TaxId:9606] [52807] (111 PDB entries)
    Uniprot P18031 2-300 ! Uniprot P18031 1-298 ! Uniprot P18031 2-299
    1. Domain for 1a5y:
    2. Domain for 1aax:
    3. Domain for 1bzc:
    4. Domain for 1bzh:
    5. Domain for 1bzj:
    6. Domain for 1c83:
    7. Domain for 1c84:
    8. Domain for 1c85:
    9. Domain for 1c86:
    10. Domain for 1c87:
    11. Domain for 1c88:
    12. Domain for 1ecv:
    13. Domain for 1een:
    14. Domain for 1eeo:
    15. Domain for 1g1f:
    16. Domain for 1g1g:
    17. Domain for 1g1h:
    18. Domain for 1g7f:
    19. Domain for 1g7g:
    20. Domain for 1gfy:
    21. Domain for 1i57:
    22. Domains for 1jf7:
      1. 1600011Domain d1jf7a_: 1jf7 A: [66619]
        complexed with tbh
      2. 1600012Domain d1jf7b_: 1jf7 B: [66620]
        complexed with tbh
    23. Domain for 1kak:
    24. Domain for 1kav:
    25. Domain for 1l8g:
    26. Domains for 1lqf:
      1. 1600044Domain d1lqfa_: 1lqf A: [74187]
        complexed with bgd
      2. 1600045Domain d1lqfb_: 1lqf B: [74188]
        complexed with bgd
      3. 1600046Domain d1lqfc_: 1lqf C: [74189]
        complexed with bgd
      4. 1600047Domain d1lqfd_: 1lqf D: [74190]
        complexed with bgd
    27. Domain for 1nl9:
    28. Domain for 1nny:
    29. Domain for 1no6:
    30. Domain for 1nwe:
    31. Domain for 1nwl:
    32. Domain for 1nz7:
    33. Domain for 1oem:
    34. Domain for 1oeo:
    35. Domain for 1oes:
    36. Domain for 1oet:
    37. Domain for 1oeu:
    38. Domain for 1oev:
    39. Domain for 1ony:
    40. Domain for 1onz:
    41. Domain for 1pa1:
    42. Domain for 1ph0:
    43. Domain for 1ptt:
    44. Domain for 1ptu:
    45. Domain for 1ptv:
    46. Domain for 1pty:
    47. Domain for 1pxh:
    48. Domain for 1pyn:
    49. Domain for 1q1m:
    50. Domain for 1q6j:
    51. Domain for 1q6m:
    52. Domains for 1q6n:
      1. 1599986Domain d1q6na_: 1q6n A: [95984]
        complexed with cl, mg, p90
      2. 1599987Domain d1q6nb_: 1q6n B: [95985]
        complexed with cl, mg, p90
    53. Domains for 1q6p:
      1. 1600020Domain d1q6pa_: 1q6p A: [95988]
        complexed with 213, cl
      2. 1600021Domain d1q6pb_: 1q6p B: [95989]
        complexed with 213, cl
    54. Domains for 1q6s:
      1. 1599997Domain d1q6sa_: 1q6s A: [95994]
        complexed with 214, cl, mg, mpd
      2. 1599998Domain d1q6sb_: 1q6s B: [95995]
        complexed with 214, cl, mg, mpd
    55. Domains for 1q6t:
      1. 1600023Domain d1q6ta_: 1q6t A: [95996]
        complexed with 600, mg
      2. 1600024Domain d1q6tb_: 1q6t B: [95997]
        complexed with 600, mg
    56. Domain for 1qxk:
    57. Domain for 1sug:
    58. Domain for 1t48:
    59. Domain for 1t49:
    60. Domain for 1t4j:
    61. Domain for 1wax:
    62. Domain for 1xbo:
    63. Domain for 2azr:
    64. Domain for 2b07:
    65. Domains for 2b4s:
      1. 1600005Domain d2b4sa_: 2b4s A: [127853]
        Other proteins in same PDB: d2b4sb_, d2b4sd_
        automated match to d1eena_
        complexed with so4
      2. 1600006Domain d2b4sc_: 2b4s C: [161389]
        Other proteins in same PDB: d2b4sb_, d2b4sd_
        automated match to d1eena_
        complexed with so4
    66. Domain for 2bgd:
    67. Domain for 2bge:
    68. Domain for 2cm7:
    69. Domain for 2cm8:
    70. Domain for 2cnf:
    71. Domain for 2cng:
    72. Domain for 2cnh:
    73. Domain for 2cni:
    74. Domain for 2f6f:
    75. Domain for 2f6t:
    76. Domain for 2f6v:
    77. Domain for 2f6w:
    78. Domain for 2f6y:
    79. Domain for 2f6z:
    80. Domain for 2f70:
    81. Domain for 2f71:
    82. Domains for 2fjm:
      1. 1599963Domain d2fjma_: 2fjm A: [204221]
        automated match to d1suga_
        complexed with 073, cl, mg
      2. 1599964Domain d2fjmb_: 2fjm B: [204222]
        automated match to d1suga_
        complexed with 073, cl, mg
    83. Domains for 2fjn:
      1. 1599994Domain d2fjna_: 2fjn A: [197918]
        automated match to d1q6sa_
        complexed with 073, cl
      2. 1599995Domain d2fjnb_: 2fjn B: [191829]
        automated match to d2f6fa_
        complexed with 073, cl
    84. Domain for 2h4g:
    85. Domain for 2h4k:
    86. Domain for 2hb1:
    87. Domain for 2hnp:
    88. Domain for 2hnq:
    89. Domain for 2nt7:
    90. Domain for 2nta:
    91. Domain for 2qbp:
    92. Domain for 2qbq:
    93. Domain for 2qbr:
    94. Domain for 2qbs:
    95. Domain for 2veu:
    96. Domain for 2vev:
    97. Domain for 2vew:
    98. Domain for 2vex:
    99. Domain for 2vey:
    100. Domain for 2zmm:
    101. Domain for 2zn7:
    102. Domain for 3cwe:
    103. Domain for 3d9c:
    104. Domain for 3eax:
    105. Domain for 3eb1:
    106. Domain for 3eu0:
    107. Domain for 3i80:
    108. Domain for 3qkp:
    109. Domain for 3qkq:
    110. Domain for 3sme:
    111. Domain for 4i8n:
  2. 1600056Human (Homo sapiens), mu [TaxId:9606] [52808] (1 PDB entry)
    receptor protein tyrosine phosphatase mu, domain 1
  3. 1600059Human (Homo sapiens), shp-1 [TaxId:9606] [52811] (4 PDB entries)
    1. Domain for 1fpr:
      • 1600062Domain d1fpra_: 1fpr A: [59949]
        complex with an in vitro peptide substrate py469 derived from shps-1, chain B
    2. Domain for 1gwz:
    3. Domain for 4gry:
    4. Domain for 4grz:
  4. 1600064Human (Homo sapiens), shp-2 [TaxId:9606] [52810] (1 PDB entry)
  5. 1600067Human (Homo sapiens), T-cell [TaxId:9606] [75233] (1 PDB entry)
    non-receptor type 2
  6. 1600069Mouse (Mus musculus) [TaxId:10090] [52809] (1 PDB entry)
    receptor protein tyrosine phosphatase alpha, domain 1
  7. 1600072Mouse (Mus musculus), ptp-sl/br7 [TaxId:10090] [64051] (1 PDB entry)

More info for Protein Tyrosine phosphatase from c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases

Timeline for Protein Tyrosine phosphatase from c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases: