SCOPe 2.07: Protein: HCV helicase domain

Lineage for Protein: HCV helicase domain

Root: SCOPe 2.07
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
division into families based on beta-sheet topologies

Family c.37.1.14: RNA helicase [52724] (4 proteins)
duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

Protein HCV helicase domain [52725] (1 species)

Species:

Human hepatitis C virus (HCV), different isolates [TaxId:11103] [52726] (17 PDB entries)
1. Domains for 1a1v:
  1. Domain d1a1va1: 1a1v A:190-325 [32467]
    protein/DNA complex; protein/RNA complex; complexed with so4
  2. Domain d1a1va2: 1a1v A:326-624 [32468]
    protein/DNA complex; protein/RNA complex; complexed with so4
2. Domains for 1cu1:
  1. Domain d1cu1a2: 1cu1 A:187-325 [32471]
    Other proteins in same PDB: d1cu1a1, d1cu1b1
    complexed with po4, zn
  2. Domain d1cu1a3: 1cu1 A:326-631 [32472]
    Other proteins in same PDB: d1cu1a1, d1cu1b1
    complexed with po4, zn
  3. Domain d1cu1b2: 1cu1 B:1187-1325 [32473]
    Other proteins in same PDB: d1cu1a1, d1cu1b1
    complexed with po4, zn
  4. Domain d1cu1b3: 1cu1 B:1326-1631 [32474]
    Other proteins in same PDB: d1cu1a1, d1cu1b1
    complexed with po4, zn
3. Domains for 1hei:
  1. Domain d1heia1: 1hei A:187-325 [32463]
    complexed with ca
  2. Domain d1heia2: 1hei A:326-629 [32464]
    complexed with ca
  3. Domain d1heib1: 1hei B:188-325 [32465]
    complexed with ca
  4. Domain d1heib2: 1hei B:326-628 [32466]
    complexed with ca
4. Domain for 1jr6:
  - Domain d1jr6a_: 1jr6 A: [71821]
    an engineered arginine-rich subdomain 2
5. Domain for 1onb:
  - Domain d1onba_: 1onb A: [87137]
    an engineered arginine-rich subdomain 2
6. Domains for 3kqh:
  1. Domain d3kqha1: 3kqh A:189-325 [212489]
    automated match to d1heia1
    protein/DNA complex
  2. Domain d3kqha2: 3kqh A:326-624 [212490]
    automated match to d1heia2
    protein/DNA complex
  3. Domain d3kqhb1: 3kqh B:189-325 [212491]
    automated match to d1heia1
    protein/DNA complex
  4. Domain d3kqhb2: 3kqh B:326-624 [212492]
    automated match to d1heia2
    protein/DNA complex
7. Domains for 3kqk:
  1. Domain d3kqka1: 3kqk A:189-325 [212493]
    automated match to d1heia1
    protein/DNA complex
  2. Domain d3kqka2: 3kqk A:326-624 [212494]
    automated match to d1heia2
    protein/DNA complex
  3. Domain d3kqkb1: 3kqk B:189-325 [212495]
    automated match to d1heia1
    protein/DNA complex
  4. Domain d3kqkb2: 3kqk B:326-624 [212496]
    automated match to d1heia2
    protein/DNA complex
8. Domains for 3kql:
  1. Domain d3kqla1: 3kql A:189-325 [212497]
    Other proteins in same PDB: d3kqla3, d3kqlb3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, alf, mg
  2. Domain d3kqla2: 3kql A:326-624 [212498]
    Other proteins in same PDB: d3kqla3, d3kqlb3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, alf, mg
  3. Domain d3kqlb1: 3kql B:189-325 [212499]
    Other proteins in same PDB: d3kqla3, d3kqlb3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, alf, mg
  4. Domain d3kqlb2: 3kql B:326-624 [212500]
    Other proteins in same PDB: d3kqla3, d3kqlb3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, alf, mg
9. Domains for 3kqn:
  1. Domain d3kqna1: 3kqn A:189-325 [212501]
    Other proteins in same PDB: d3kqna3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  2. Domain d3kqna2: 3kqn A:326-624 [212502]
    Other proteins in same PDB: d3kqna3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
10. Domains for 3kqu:
  1. Domain d3kqua1: 3kqu A:189-325 [212503]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  2. Domain d3kqua2: 3kqu A:326-624 [212504]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
  3. Domain d3kqub1: 3kqu B:189-325 [212505]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  4. Domain d3kqub2: 3kqu B:326-624 [212506]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
  5. Domain d3kquc1: 3kqu C:189-325 [212507]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  6. Domain d3kquc2: 3kqu C:326-624 [212508]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
  7. Domain d3kqud1: 3kqu D:189-325 [212509]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  8. Domain d3kqud2: 3kqu D:326-624 [212510]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
  9. Domain d3kque1: 3kqu E:189-325 [212511]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  10. Domain d3kque2: 3kqu E:326-624 [212512]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
  11. Domain d3kquf1: 3kqu F:189-325 [212513]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia1
    protein/DNA complex; complexed with adp, bef, mn
  12. Domain d3kquf2: 3kqu F:326-624 [212514]
    Other proteins in same PDB: d3kqua3, d3kqub3, d3kquc3, d3kqud3, d3kque3, d3kquf3
    automated match to d1heia2
    protein/DNA complex; complexed with adp, bef, mn
11. Domains for 3rvb:
  1. Domain d3rvba1: 3rvb A:186-325 [260019]
    automated match to d1cu1a2
    complexed with cl, i79, mg
  2. Domain d3rvba2: 3rvb A:326-630 [260021]
    automated match to d1cu1a3
    complexed with cl, i79, mg
12. Domains for 4ojq:
  1. Domain d4ojqa1: 4ojq A:186-325 [237405]
    automated match to d1cu1a2
    complexed with 2sx, ca
  2. Domain d4ojqa2: 4ojq A:326-630 [237406]
    automated match to d1cu1a3
    complexed with 2sx, ca
  3. Domain d4ojqb1: 4ojq B:187-325 [237409]
    automated match to d1cu1a2
    complexed with 2sx, ca
  4. Domain d4ojqb2: 4ojq B:326-628 [237410]
    automated match to d1cu1a3
    complexed with 2sx, ca
13. Domains for 4ok3:
  1. Domain d4ok3a1: 4ok3 A:187-325 [238286]
    automated match to d4ojqa1
    complexed with 2sy, ca
  2. Domain d4ok3a2: 4ok3 A:326-629 [238287]
    automated match to d4ojqa2
    complexed with 2sy, ca
  3. Domain d4ok3b1: 4ok3 B:187-325 [238284]
    automated match to d4ojqa1
    complexed with 2sy, ca
  4. Domain d4ok3b2: 4ok3 B:326-628 [238285]
    automated match to d4ojqa2
    complexed with 2sy, ca
14. Domains for 4ok5:
  1. Domain d4ok5a1: 4ok5 A:184-325 [238292]
    automated match to d4ojqa1
    complexed with 2t2, ca
  2. Domain d4ok5a2: 4ok5 A:326-629 [238293]
    automated match to d4ojqa2
    complexed with 2t2, ca
  3. Domain d4ok5b1: 4ok5 B:187-325 [238294]
    automated match to d4ojqa1
    complexed with 2t2, ca
  4. Domain d4ok5b2: 4ok5 B:326-629 [238295]
    automated match to d4ojqa2
    complexed with 2t2, ca
15. Domains for 4ok6:
  1. Domain d4ok6a1: 4ok6 A:185-325 [237407]
    automated match to d1cu1a2
    complexed with 2t7, ca
  2. Domain d4ok6b1: 4ok6 B:187-325 [238288]
    automated match to d4ojqa1
    complexed with 2t7, ca
  3. Domain d4ok6b2: 4ok6 B:326-627 [238289]
    automated match to d4ojqa2
    complexed with 2t7, ca
16. Domains for 4oks:
  1. Domain d4oksa1: 4oks A:184-325 [237408]
    automated match to d1cu1a2
    complexed with 2t9, ca
  2. Domain d4oksb1: 4oks B:187-325 [238290]
    automated match to d4ojqa1
    complexed with 2t9, ca
  3. Domain d4oksb2: 4oks B:326-630 [238291]
    automated match to d4ojqa2
    complexed with 2t9, ca
17. Domains for 8ohm:
  1. Domain d8ohma1: 8ohm A:190-325 [32469]
  2. Domain d8ohma2: 8ohm A:326-624 [32470]

More info for Protein HCV helicase domain from c.37.1.14: RNA helicase

Timeline for Protein HCV helicase domain from c.37.1.14: RNA helicase:

Protein HCV helicase domain from c.37.1.14: RNA helicase first appeared (with stable ids) in SCOP 1.55
Protein HCV helicase domain from c.37.1.14: RNA helicase appears in SCOPe 2.06
Protein HCV helicase domain from c.37.1.14: RNA helicase does not appear in SCOPe 2.08