SCOP 1.75: Family c.37.1.1: Nucleotide and nucleoside kinases

Lineage for Family c.37.1.1: Nucleotide and nucleoside kinases

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (20 proteins)
   parallel beta-sheet of 5 strands, order 23145

Proteins:

1. 5' polynucleotide kinase-3' phosphatase, C-terminal domain [142213] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [142214] (1 PDB entry)
     Uniprot Q9JLV6 351-522

2. Adenylate kinase [52554] (14 species)

   1. Species Archaeon Methanococcus thermolithotrophicus [TaxId:2186] [89661] (1 PDB entry)

   2. Species Archaeon Methanococcus voltae [TaxId:2188] [89660] (1 PDB entry)

   3. Species Archaeon Sulfolobus acidocaldarius [TaxId:2285] [52556] (1 PDB entry)

   4. Species Bacillus globisporus [TaxId:1459] [102342] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160

   5. Species Bacillus stearothermophilus [TaxId:1422] [52562] (3 PDB entries)
      contains a zinc-finger subdomain, residues 126-160

   6. Species Bacillus subtilis [TaxId:1423] [102341] (1 PDB entry)
      contains a zinc-finger subdomain, residues 126-160

   7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52559] (4 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 131-168

   8. Species Cow (Bos taurus), mitochondrial izozyme-2 [TaxId:9913] [52558] (2 PDB entries)
      contains a rudiment "zinc-finger" subdomain, residue 147-176

   9. Species Cow (Bos taurus), mitochondrial izozyme-3 [TaxId:9913] [52557] (1 PDB entry)
      contains a rudiment "zinc-finger" subdomain, residue 125-161

   10. Species Escherichia coli [TaxId:562] [52560] (6 PDB entries)
       contains a rudiment "zinc-finger" subdomain, residue 122-156

   11. Species Human (Homo sapiens), isoenzyme 6 [TaxId:9606] [117527] (1 PDB entry)
       Uniprot Q9Y3D8

   12. Species Maize (Zea mays) [TaxId:4577] [52561] (1 PDB entry)

   13. Species Mycobacterium tuberculosis [TaxId:1773] [102343] (2 PDB entries)
       contains no zinc finger-like insertion

   14. Species Pig (Sus scrofa) [TaxId:9823] [52555] (1 PDB entry)

3. CMP kinase [52548] (2 species)

   1. Species Escherichia coli [TaxId:562] [52549] (6 PDB entries)

   2. Species Streptococcus pneumoniae [TaxId:1313] [110525] (1 PDB entry)
      Uniprot Q97PK6

4. Deoxycytidine kinase [89657] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [89658] (7 PDB entries)

5. Deoxyguanosine kinase [69480] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69481] (1 PDB entry)

6. Deoxynucleoside monophosphate kinase [52546] (1 species)
   contains insert 4-helical bundle subdomain, residues 35-145

   • Species Bacteriophage T4 [TaxId:10665] [52547] (2 PDB entries)

7. Deoxyribonucleoside kinase [69478] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [69479] (11 PDB entries)

8. Dephospho-CoA kinase [75187] (3 species)

   1. Species Escherichia coli [TaxId:562] [82394] (5 PDB entries)

   2. Species Haemophilus influenzae [TaxId:727] [75188] (1 PDB entry)

   3. Species Thermus thermophilus [TaxId:274] [102344] (1 PDB entry)
      TT1252

9. Guanylate kinase [52542] (4 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52543] (3 PDB entries)

   2. Species Escherichia coli [TaxId:562] [102338] (6 PDB entries)

   3. Species Mouse (Mus musculus) [TaxId:10090] [82393] (1 PDB entry)

   4. Species Mycobacterium tuberculosis [TaxId:1773] [102339] (5 PDB entries)
      Rv1389

10. Guanylate kinase-like domain of Cask [69474] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [69475] (1 PDB entry)

11. Guanylate kinase-like domain of Psd-95 [69476] (1 species)

    • Species Rat (Rattus norvegicus) [TaxId:10116] [69477] (3 PDB entries)

12. Guanylate kinase-like domain of the L-type calcium channel [110527] (2 species)

    1. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110528] (4 PDB entries)
       Uniprot P54288 234-451

    2. Species Rat (Rattus norvegicus) [TaxId:10116] [110529] (3 PDB entries)
       Uniprot P54287 38-362

13. Hypothetical protein YorR [142211] (1 species)

    • Species Bacillus subtilis [TaxId:1423] [142212] (1 PDB entry)
      Uniprot O31896 2-165

14. Polynucleotide kinase, kinase domain [75191] (1 species)

    • Species Bacteriophage T4 [TaxId:10665] [75192] (6 PDB entries)

15. Probable kinase LmjF30.1890 [117528] (1 species)

    • Species Leishmania major [TaxId:5664] [117529] (1 PDB entry)
      Uniprot Q4Q7A6

16. Thymidine kinase [52552] (3 species)
    contains insert all-alpha subdomain, res. 251-322

    1. Species Equine herpesvirus type 4 [TaxId:10331] [102340] (4 PDB entries)

    2. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (22 PDB entries)
       Uniprot P03176 46-375

    3. Species Varicella-zoster virus [TaxId:10335] [89659] (1 PDB entry)

17. Thymidylate kinase [52563] (4 species)

    1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52564] (3 PDB entries)

    2. Species Escherichia coli [TaxId:562] [52565] (2 PDB entries)

    3. Species Human (Homo sapiens) [TaxId:9606] [64010] (20 PDB entries)

    4. Species Mycobacterium tuberculosis [TaxId:1773] [69482] (11 PDB entries)

18. Transcriptional regulator NadR, ribosylnicotinamide kinase domain [75189] (1 species)

    • Species Haemophilus influenzae [TaxId:727] [75190] (1 PDB entry)

19. UMP/CMP kinase [52550] (2 species)

    1. Species Dictyostelium discoideum [TaxId:44689] [52551] (6 PDB entries)

    2. Species Human (Homo sapiens) [TaxId:9606] [110526] (1 PDB entry)
       Uniprot P30085

20. Uridylate kinase [52544] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52545] (2 PDB entries)

More info for Family c.37.1.1: Nucleotide and nucleoside kinases

Timeline for Family c.37.1.1: Nucleotide and nucleoside kinases:

• Family c.37.1.1: Nucleotide and nucleoside kinases first appeared (with stable ids) in SCOP 1.55
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in SCOP 1.73
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in SCOPe 2.01
  
• Family c.37.1.1: Nucleotide and nucleoside kinases appears in the current release, SCOPe 2.08