Lineage for Protein: Branched-chain alpha-keto acid dehydrogenase, PP and Pyr modules

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 242757Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 242758Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (4 families) (S)
    both pyridine (Pyr)- and pyrophosphate (PP)-binding modules have this fold
    conserved core consists of two Pyr and two PP-modules and binds two coenzyme molecules
  5. 242884Family c.36.1.3: Branched-chain alpha-keto acid dehydrogenase THDP-binding domains [52531] (3 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 242889Protein Branched-chain alpha-keto acid dehydrogenase, PP and Pyr modules [52532] (1 species)

Species:

More info for Protein Branched-chain alpha-keto acid dehydrogenase, PP and Pyr modules from c.36.1.3: Branched-chain alpha-keto acid dehydrogenase THDP-binding domains

Timeline for Protein Branched-chain alpha-keto acid dehydrogenase, PP and Pyr modules from c.36.1.3: Branched-chain alpha-keto acid dehydrogenase THDP-binding domains: