SCOPe 2.03: Protein: Pyruvate oxidase

Lineage for Protein: Pyruvate oxidase

Root: SCOPe 2.03
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold
Protein Pyruvate oxidase [52476] (2 species)
binds FAD

Species:

Aerococcus viridans [TaxId:1377] [142122] (4 PDB entries)
1. Domain for 1v5e:
  - Domain d1v5ea1: 1v5e A:187-363 [119844]
    Other proteins in same PDB: d1v5ea2, d1v5ea3
    complexed with fad, so4
2. Domain for 1v5f:
  - Domain d1v5fa1: 1v5f A:187-363 [119847]
    Other proteins in same PDB: d1v5fa2, d1v5fa3
    automatically matched to 1V5E A:187-363
    complexed with fad, mg, so4, tpp
3. Domain for 1v5g:
  - Domain d1v5ga1: 1v5g A:187-363 [119850]
    Other proteins in same PDB: d1v5ga2, d1v5ga3
    automatically matched to 1V5E A:187-363
    complexed with fad, htl, mg
4. Domain for 2dji:
  - Domain d2djia1: 2dji A:187-363 [131544]
    Other proteins in same PDB: d2djia2, d2djia3
    automated match to d1v5ea1
    complexed with fad, so4
Lactobacillus plantarum [TaxId:1590] [52477] (7 PDB entries)
1. Domains for 1pow:
  1. Domain d1powa1: 1pow A:183-365 [31733]
    Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
    complexed with fad, mg, tpp; mutant
  2. Domain d1powb1: 1pow B:183-365 [31734]
    Other proteins in same PDB: d1powa2, d1powa3, d1powb2, d1powb3
    complexed with fad, mg, tpp; mutant
2. Domains for 1pox:
  1. Domain d1poxa1: 1pox A:183-365 [31731]
    Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
    complexed with fad, gol, mg, na, tpp; mutant
  2. Domain d1poxb1: 1pox B:183-365 [31732]
    Other proteins in same PDB: d1poxa2, d1poxa3, d1poxb2, d1poxb3
    complexed with fad, gol, mg, na, tpp; mutant
3. Domains for 2ez4:
  1. Domain d2ez4a1: 2ez4 A:183-365 [132610]
    Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
    automatically matched to d1powa1
    complexed with fad, mg, na, po4, tpp
  2. Domain d2ez4b1: 2ez4 B:183-365 [132613]
    Other proteins in same PDB: d2ez4a2, d2ez4a3, d2ez4b2, d2ez4b3
    automatically matched to d1powa1
    complexed with fad, mg, na, po4, tpp
4. Domains for 2ez8:
  1. Domain d2ez8a1: 2ez8 A:183-365 [132621]
    Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
    automatically matched to d1powa1
    complexed with fad, mg, na, pyr, tdl
  2. Domain d2ez8b1: 2ez8 B:183-365 [132624]
    Other proteins in same PDB: d2ez8a2, d2ez8a3, d2ez8b2, d2ez8b3
    automatically matched to d1powa1
    complexed with fad, mg, na, pyr, tdl
5. Domains for 2ez9:
  1. Domain d2ez9a1: 2ez9 A:183-365 [132627]
    Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
    automatically matched to d1powa1
    complexed with fad, mg, na, tdk
  2. Domain d2ez9b1: 2ez9 B:183-365 [132630]
    Other proteins in same PDB: d2ez9a2, d2ez9a3, d2ez9b2, d2ez9b3
    automatically matched to d1powa1
    complexed with fad, mg, na, tdk
6. Domains for 2ezt:
  1. Domain d2ezta1: 2ezt A:183-365 [132633]
    Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
    automatically matched to d1powa1
    complexed with fad, mg, na, po4, pyr, tdm
  2. Domain d2eztb1: 2ezt B:183-365 [132636]
    Other proteins in same PDB: d2ezta2, d2ezta3, d2eztb2, d2eztb3
    automatically matched to d1powa1
    complexed with fad, mg, na, po4, pyr, tdm
7. Domains for 2ezu:
  1. Domain d2ezua1: 2ezu A:183-365 [132639]
    Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
    automatically matched to d1powa1
    complexed with fad, htl, mg, na, pyr
  2. Domain d2ezub1: 2ezu B:183-365 [132642]
    Other proteins in same PDB: d2ezua2, d2ezua3, d2ezub2, d2ezub3
    automatically matched to d1powa1
    complexed with fad, htl, mg, na, pyr

More info for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain:

Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain first appeared (with stable ids) in SCOP 1.55
Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.02
Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in SCOPe 2.04
Protein Pyruvate oxidase from c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain appears in the current release, SCOPe 2.08