Lineage for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2121033Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2121034Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2121061Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain [52475] (8 proteins)
    N-terminal domain is Pyr module, and C-terminal domain is PP module of thiamin diphosphate-binding fold

Proteins:

  1. 2121062Acetohydroxyacid synthase catalytic subunit [69463] (3 species)
    1. 2121063Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [69464] (10 PDB entries)
      Uniprot P07342 84-687
    2. 2121086Species Saccharomyces cerevisiae [TaxId:559292] [314108] (2 PDB entries)
    3. 2121091Species Thale cress (Arabidopsis thaliana), chloroplast [TaxId:3702] [142123] (11 PDB entries)
      Uniprot P17597 281-459
  2. 2121103Benzoylformate decarboxylase [52482] (1 species)
  3. 2121185Carboxyethylarginine synthase [102290] (1 species)
  4. 2121213Catabolic acetolactate synthase [102288] (1 species)
  5. 2121223Indole-3-pyruvate decarboxylase [89637] (1 species)
  6. 2121229Oxalyl-CoA decarboxylase [142124] (1 species)
  7. 2121243Pyruvate decarboxylase [52478] (3 species)
    rudiment domain with a variant fold, lacks FAD-binding
    1. 2121244Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [52480] (2 PDB entries)
    2. 2121249Species Brewer's yeast (Saccharomyces uvarum) [TaxId:230603] [52479] (1 PDB entry)
    3. 2121252Species Zymomonas mobilis [TaxId:542] [52481] (1 PDB entry)
  8. 2121257Pyruvate oxidase [52476] (2 species)
    binds FAD
    1. 2121258Species Aerococcus viridans [TaxId:1377] [142122] (2 PDB entries)
    2. 2121261Species Lactobacillus plantarum [TaxId:1590] [52477] (8 PDB entries)

More info for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain

Timeline for Family c.31.1.3: Pyruvate oxidase and decarboxylase, middle domain: