SCOPe 2.05: Protein: Thymidine phosphorylase

Root: SCOPe 2.05
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.27: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52417] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32145; Rossmann-like
Superfamily c.27.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52418] (2 families)
automatically mapped to Pfam PF00591
Family c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52419] (4 proteins)
Protein Thymidine phosphorylase [52420] (2 species)

Escherichia coli [TaxId:562] [52421] (7 PDB entries)
1. Domains for 1azy:
  1. Domain d1azya2: 1azy A:71-335 [31625]
    Other proteins in same PDB: d1azya1, d1azya3, d1azyb1, d1azyb3
  2. Domain d1azyb2: 1azy B:71-335 [31626]
    Other proteins in same PDB: d1azya1, d1azya3, d1azyb1, d1azyb3
2. Domain for 1otp:
  - Domain d1otpa2: 1otp A:71-335 [31624]
    Other proteins in same PDB: d1otpa1, d1otpa3
3. Domain for 1tpt:
  - Domain d1tpta2: 1tpt A:71-335 [31627]
    Other proteins in same PDB: d1tpta1, d1tpta3
    complexed with so4, tdr
4. Domain for 2tpt:
  - Domain d2tpta2: 2tpt A:71-335 [31623]
    Other proteins in same PDB: d2tpta1, d2tpta3
    complexed with so4
5. Domain for 4ead:
  - Domain d4eada2: 4ead A:71-335 [220386]
    Other proteins in same PDB: d4eada1, d4eada3
    automated match to d2tpta2
    complexed with 0np, gol, so4
6. Domain for 4eaf:
  - Domain d4eafa2: 4eaf A:71-335 [220389]
    Other proteins in same PDB: d4eafa1, d4eafa3
    automated match to d2tpta2
    complexed with gol, so4
7. Domain for 4lhm:
  - Domain d4lhma2: 4lhm A:71-335 [238427]
    Other proteins in same PDB: d4lhma1, d4lhma3
    automated match to d2tpta2
    complexed with azz, gol, so4
Human (Homo sapiens) [TaxId:9606] [102268] (1 PDB entry)
- Domain for 1uou:
  - Domain d1uoua2: 1uou A:101-373 [99707]
    Other proteins in same PDB: d1uoua1, d1uoua3
    complexed with cmu

Timeline for Protein Thymidine phosphorylase from c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain:

Protein Thymidine phosphorylase from c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain first appeared (with stable ids) in SCOP 1.55, called Protein Thymidine phosphorylase from c.27.1.1: Pyrimidine nucleoside phosphorylase central domain
Protein Thymidine phosphorylase from c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain appears in SCOPe 2.04
Protein Thymidine phosphorylase from c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain appears in SCOPe 2.06
Protein Thymidine phosphorylase from c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain appears in the current release, SCOPe 2.08