SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family c.6.1.1: Glycosyl hydrolases family 6, cellulases

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2097504Fold c.6: 7-stranded beta/alpha barrel [51988] (3 superfamilies)
    variant of beta/alpha barrel; parallel beta-sheet barrel, closed, n=7, S=8; strand order 1234567; some members may have fewer strands
  4. 2097505Superfamily c.6.1: Glycosyl hydrolases family 6, cellulases [51989] (2 families) (S)
  5. 2097506Family c.6.1.1: Glycosyl hydrolases family 6, cellulases [51990] (4 protein domains)
    Pfam PF01341

Protein Domains:

  1. 2097507Cellobiohydrolase II (Cel6) [51993] (3 species)
    1. 2097508Species Humicola insolens, Cel6a [TaxId:34413] [51995] (9 PDB entries)
    2. 2097520Species Humicola insolens, Cel6b [TaxId:34413] [51996] (1 PDB entry)
    3. 2097523Species Trichoderma reesei, Cel6a [TaxId:51453] [51994] (7 PDB entries)
  2. 2097537Cellulase E2 [51991] (1 species)
  3. 2097544Putative cellulase Rv0062 (Cel6, CelA1) [117447] (1 species)
  4. 2097550automated matches [191253] (7 species)
    not a true protein
    1. 2097551Species Chaetomium thermophilum [TaxId:209285] [194920] (1 PDB entry)
    2. 2097553Species Fungus (Humicola insolens) [TaxId:34413] [196744] (2 PDB entries)
    3. 2097556Species Human (Homo sapiens) [TaxId:9606] [189788] (1 PDB entry)
    4. 2097558Species Hypocrea jecorina [TaxId:51453] [194099] (1 PDB entry)
    5. 2097561Species Thermobifida fusca [TaxId:2021] [190013] (1 PDB entry)
    6. 2097564Species Trichoderma reesei [TaxId:51453] [194094] (2 PDB entries)
    7. 2293828Species Phanerochaete chrysosporium [TaxId:5306] [337129] (2 PDB entries)

More info for Family c.6.1.1: Glycosyl hydrolases family 6, cellulases

Timeline for Family c.6.1.1: Glycosyl hydrolases family 6, cellulases: