SCOP 1.75: Protein: Thioredoxin reductase

Lineage for Protein: Thioredoxin reductase

Root: SCOP 1.75
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (8 families)

Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 proteins)
duplication: both domains have similar folds and functions
most members of the family contain common C-terminal alpha+beta domain

Protein Thioredoxin reductase [51950] (2 species)
lacks the "interface" C-terminal alpha+beta domain

Species:

Escherichia coli [TaxId:562] [51951] (5 PDB entries)
1. Domains for 1cl0:
  1. Domain d1cl0a1: 1cl0 A:1-118,A:245-317 [30535]
  2. Domain d1cl0a2: 1cl0 A:119-244 [30536]
2. Domains for 1f6m:
  1. Domain d1f6ma1: 1f6m A:1-118,A:245-320 [30537]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  2. Domain d1f6ma2: 1f6m A:119-244 [30538]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  3. Domain d1f6mb1: 1f6m B:1-118,B:245-320 [30539]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  4. Domain d1f6mb2: 1f6m B:119-244 [30540]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  5. Domain d1f6me1: 1f6m E:1-118,E:245-320 [30541]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  6. Domain d1f6me2: 1f6m E:119-244 [30542]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  7. Domain d1f6mf1: 1f6m F:1-118,F:245-320 [30543]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
  8. Domain d1f6mf2: 1f6m F:119-244 [30544]
    Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
    complexed with thioredoxin
    complexed with 3aa, fad; mutant
3. Domains for 1tde:
  1. Domain d1tdea1: 1tde A:1-118,A:245-316 [30531]
  2. Domain d1tdea2: 1tde A:119-244 [30532]
    complexed with fad
4. Domains for 1tdf:
  1. Domain d1tdfa1: 1tdf A:1-118,A:245-316 [30533]
  2. Domain d1tdfa2: 1tdf A:119-244 [30534]
    complexed with fad, nap; mutant
5. Domains for 1trb:
  1. Domain d1trba1: 1trb A:1-118,A:245-316 [30529]
  2. Domain d1trba2: 1trb A:119-244 [30530]
    complexed with fad; mutant
Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [51952] (1 PDB entry)
- Domains for 1vdc:
  1. Domain d1vdca1: 1vdc A:1-117,A:244-316 [30545]
  2. Domain d1vdca2: 1vdc A:118-243 [30546]
    complexed with fad, so4

More info for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains:

Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains first appeared (with stable ids) in SCOP 1.55
Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in SCOP 1.73
Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in SCOPe 2.01
Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in the current release, SCOPe 2.08