Lineage for Protein: Thioredoxin reductase

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 388822Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 388823Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families) (S)
  5. 389137Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (12 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 389316Protein Thioredoxin reductase [51950] (2 species)
    lacks the "interface" C-terminal alpha+beta domain

Species:

  1. 389317Escherichia coli [TaxId:562] [51951] (5 PDB entries)
    1. Domains for 1cl0:
      1. 389320Domain d1cl0a1: 1cl0 A:1-118,A:245-317 [30535]
      2. 389321Domain d1cl0a2: 1cl0 A:119-244 [30536]
    2. Domains for 1f6m:
      1. 389326Domain d1f6ma1: 1f6m A:1-118,A:245-320 [30537]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      2. 389327Domain d1f6ma2: 1f6m A:119-244 [30538]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      3. 389328Domain d1f6mb1: 1f6m B:1-118,B:245-320 [30539]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      4. 389329Domain d1f6mb2: 1f6m B:119-244 [30540]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      5. 389330Domain d1f6me1: 1f6m E:1-118,E:245-320 [30541]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      6. 389331Domain d1f6me2: 1f6m E:119-244 [30542]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      7. 389332Domain d1f6mf1: 1f6m F:1-118,F:245-320 [30543]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
      8. 389333Domain d1f6mf2: 1f6m F:119-244 [30544]
        Other proteins in same PDB: d1f6mc_, d1f6md_, d1f6mg_, d1f6mh_
        complexed with thioredoxin
        complexed with 3aa, fad; mutant
    3. Domains for 1tde:
      1. 389322Domain d1tde_1: 1tde 1-118,245-316 [30531]
      2. 389323Domain d1tde_2: 1tde 119-244 [30532]
        complexed with fad
    4. Domains for 1tdf:
      1. 389324Domain d1tdf_1: 1tdf 1-118,245-316 [30533]
      2. 389325Domain d1tdf_2: 1tdf 119-244 [30534]
        complexed with fad, nap; mutant
    5. Domains for 1trb:
      1. 389318Domain d1trb_1: 1trb 1-118,245-316 [30529]
      2. 389319Domain d1trb_2: 1trb 119-244 [30530]
        complexed with fad; mutant
  2. 389334Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [51952] (1 PDB entry)

More info for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Thioredoxin reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains: