Lineage for Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 239501Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 239502Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families) (S)
  5. 239750Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (12 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain

Proteins:

  1. 239751Alkyl hydroperoxide reductase subunit F (AhpF), C-terminal domains [51953] (2 species)
    1. 239752Species Escherichia coli [TaxId:562] [63949] (1 PDB entry)
    2. 239755Species Salmonella typhimurium [TaxId:90371] [51954] (1 PDB entry)
  2. 239758Apoptosis-inducing factor (AIF) [75126] (2 species)
    1. 239759Species Human (Homo sapiens) [TaxId:9606] [75127] (1 PDB entry)
    2. 239762Species Mouse (Mus musculus) [TaxId:10090] [75128] (1 PDB entry)
  3. 239767Dihydrolipoamide dehydrogenase [51959] (7 species)
    1. 239768Species Azotobacter vinelandii [TaxId:354] [51962] (1 PDB entry)
    2. 239773Species Bacillus stearothermophilus [TaxId:1422] [51963] (1 PDB entry)
    3. 239778Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [63950] (1 PDB entry)
    4. 239783Species Garden pea (Pisum sativum) [TaxId:3888] [51965] (1 PDB entry)
    5. 239792Species Neisseria meningitidis [TaxId:487] [51964] (2 PDB entries)
    6. 239797Species Pseudomonas fluorescens [TaxId:294] [51961] (1 PDB entry)
    7. 239802Species Pseudomonas putida [TaxId:303] [51960] (1 PDB entry)
  4. 239805Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit [51966] (1 species)
    has a smaller C-terminal alpha+beta domain instead the "interface" domain
  5. 239811Glutathione reductase [51944] (2 species)
    1. 239812Species Escherichia coli [TaxId:562] [51946] (4 PDB entries)
    2. 239829Species Human (Homo sapiens) [TaxId:9606] [51945] (17 PDB entries)
  6. 239864Mammalian thioredoxin reductase [63947] (1 species)
  7. Mercuric ion reductase [51968] (1 species)
  8. 239881NADH peroxidase [51955] (1 species)
  9. 239899NADH-dependent 2-ketopropyl coenzyme M oxidoreductase/carboxylase [82313] (1 species)
  10. 239913NADH-dependent ferredoxin reductase, BphA4 [51957] (1 species)
  11. 239919Thioredoxin reductase [51950] (2 species)
    lacks the "interface" C-terminal alpha+beta domain
    1. 239920Species Escherichia coli [TaxId:562] [51951] (5 PDB entries)
    2. 239937Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [51952] (1 PDB entry)
  12. 239940Trypanothione reductase [51947] (2 species)
    1. 239941Species Crithidia fasciculata [TaxId:5656] [51948] (6 PDB entries)
    2. 239970Species Trypanosoma cruzi [TaxId:5693] [51949] (3 PDB entries)

More info for Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains: