SCOP 1.65: Family c.3.1.2: FAD-linked reductases, N-terminal domain

Lineage for Family c.3.1.2: FAD-linked reductases, N-terminal domain

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families)

5. Family c.3.1.2: FAD-linked reductases, N-terminal domain [51913] (11 proteins)
   C-terminal domain is alpha+beta is common for the family

Proteins:

1. Cholesterol oxidase of GMC family [51914] (2 species)

   1. Species Brevibacterium sterolicum [TaxId:1702] [51915] (2 PDB entries)

   2. Species Streptomyces sp. [TaxId:1931] [51916] (6 PDB entries)

2. Flavoprotein domain of flavocytochrome cellobiose dehydrogenase (CDH), FAD-binding domain [82309] (1 species)

   • Species Fungus (Phanerochaete chrysosporium) [TaxId:5306] [82310] (2 PDB entries)

3. Glucose oxidase [51924] (2 species)

   1. Species Aspergillus niger [51925] (2 PDB entries)

   2. Species Penicillium amagasakiense [TaxId:63559] [51926] (1 PDB entry)

4. Glycine oxidase ThiO [89544] (1 species)

   • Species Bacillus sp. [89545] (2 PDB entries)

5. Hydroxynitrile lyase [82307] (1 species)

   • Species Almond (Prunus dulcis) [TaxId:3755] [82308] (1 PDB entry)

6. L-aminoacid oxidase [51929] (1 species)

   • Species Malayan pit viper (Calloselasma rhodostoma) [TaxId:8717] [51930] (2 PDB entries)

7. Monoamine oxidase B [69423] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69424] (1 PDB entry)

8. p-Hydroxybenzoate hydroxylase, PHBH [51917] (2 species)

   1. Species Pseudomonas aeruginosa [TaxId:287] [51919] (17 PDB entries)

   2. Species Pseudomonas fluorescens [TaxId:294] [51918] (17 PDB entries)

9. Phenol hydroxylase [51922] (1 species)
   structurally very similar to PHBH, but contains additional C-terminal domain of the thioredoxin-like fold

   • Species Soil-living yeast (Trichosporon cutaneum) [TaxId:5554] [51923] (1 PDB entry)

10. Polyamine oxidase [51927] (1 species)

    • Species Maize (Zea mays) [TaxId:4577] [51928] (7 PDB entries)

11. Sarcosine oxidase [51920] (1 species)

    • Species Bacillus sp., strain b0618 [TaxId:1409] [51921] (9 PDB entries)

More info for Family c.3.1.2: FAD-linked reductases, N-terminal domain

Timeline for Family c.3.1.2: FAD-linked reductases, N-terminal domain:

• Family c.3.1.2: FAD-linked reductases, N-terminal domain first appeared (with stable ids) in SCOP 1.55
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in SCOP 1.63
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in SCOP 1.67
  
• Family c.3.1.2: FAD-linked reductases, N-terminal domain appears in the current release, SCOPe 2.08