SCOPe 2.08: Protein: 6-phosphogluconate dehydrogenase

Lineage for Protein: 6-phosphogluconate dehydrogenase

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (19 proteins)
the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
C-terminal domains also show some similarity

Protein 6-phosphogluconate dehydrogenase [51871] (2 species)

Species:

Sheep (Ovis orientalis aries) [TaxId:9940] [51872] (5 PDB entries)
1. Domain for 1pgn:
  - Domain d1pgna2: 1pgn A:1-176 [30193]
    Other proteins in same PDB: d1pgna1
    complexed with nbp, pop, so4
2. Domain for 1pgo:
  - Domain d1pgoa2: 1pgo A:1-176 [30191]
    Other proteins in same PDB: d1pgoa1
    complexed with ndp, so4
3. Domain for 1pgp:
  - Domain d1pgpa2: 1pgp A:1-176 [30192]
    Other proteins in same PDB: d1pgpa1
    complexed with 6pg, so4
4. Domain for 1pgq:
  - Domain d1pgqa2: 1pgq A:1-176 [30194]
    Other proteins in same PDB: d1pgqa1
    complexed with 2am, so4
5. Domain for 2pgd:
  - Domain d2pgda2: 2pgd A:1-176 [30190]
    Other proteins in same PDB: d2pgda1
    complexed with so4
Trypanosome (Trypanosoma brucei) [TaxId:5691] [51873] (1 PDB entry)
- Domains for 1pgj:
  1. Domain d1pgja2: 1pgj A:1-178 [30195]
    Other proteins in same PDB: d1pgja1, d1pgjb1
    complexed with so4
  2. Domain d1pgjb2: 1pgj B:1-178 [30196]
    Other proteins in same PDB: d1pgja1, d1pgjb1
    complexed with so4

More info for Protein 6-phosphogluconate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Timeline for Protein 6-phosphogluconate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:

Protein 6-phosphogluconate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55
Protein 6-phosphogluconate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOPe 2.07