SCOP 1.73: Protein: Class II ketol-acid reductoisomerase (KARI)

Lineage for Protein: Class II ketol-acid reductoisomerase (KARI)

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (17 proteins)
the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
C-terminal domains also show some similarity

Protein Class II ketol-acid reductoisomerase (KARI) [51869] (1 species)
contains additional subdomain at the N-terminus, partly ordered

Species:

Spinach (Spinacia oleracea) [TaxId:3562] [51870] (2 PDB entries)
1. Domains for 1qmg:
  1. Domain d1qmga2: 1qmg A:82-307 [30182]
    Other proteins in same PDB: d1qmga1, d1qmgb1, d1qmgc1, d1qmgd1
  2. Domain d1qmgb2: 1qmg B:86-307 [30183]
    Other proteins in same PDB: d1qmga1, d1qmgb1, d1qmgc1, d1qmgd1
  3. Domain d1qmgc2: 1qmg C:84-307 [30184]
    Other proteins in same PDB: d1qmga1, d1qmgb1, d1qmgc1, d1qmgd1
  4. Domain d1qmgd2: 1qmg D:83-307 [30185]
    Other proteins in same PDB: d1qmga1, d1qmgb1, d1qmgc1, d1qmgd1
    complexed with apx, dmv, mn, so4
2. Domains for 1yve:
  1. Domain d1yvei2: 1yve I:83-307 [30186]
    Other proteins in same PDB: d1yvei1, d1yvej1, d1yvek1, d1yvel1
  2. Domain d1yvej2: 1yve J:86-307 [30187]
    Other proteins in same PDB: d1yvei1, d1yvej1, d1yvek1, d1yvel1
  3. Domain d1yvek2: 1yve K:86-307 [30188]
    Other proteins in same PDB: d1yvei1, d1yvej1, d1yvek1, d1yvel1
  4. Domain d1yvel2: 1yve L:83-307 [30189]
    Other proteins in same PDB: d1yvei1, d1yvej1, d1yvek1, d1yvel1
    complexed with cl, hio, mg, ndp

More info for Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Timeline for Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:

Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain first appeared (with stable ids) in SCOP 1.55, called Protein Acetohydroxy acid isomeroreductase, ketoacid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain
Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOP 1.71
Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOP 1.75
Protein Class II ketol-acid reductoisomerase (KARI) from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.08