Lineage for Protein: Lactate dehydrogenase

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 387036Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 387037Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families) (S)
  5. 388231Family c.2.1.5: LDH N-terminal domain-like [51848] (7 proteins)
  6. 388242Protein Lactate dehydrogenase [51859] (13 species)

Species:

  1. 388243Bacillus stearothermophilus [TaxId:1422] [51864] (3 PDB entries)
    1. Domain for 1ldb:
    2. Domains for 1ldn:
      1. 388244Domain d1ldna1: 1ldn A:15-162 [30166]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      2. 388245Domain d1ldnb1: 1ldn B:15-162 [30167]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      3. 388246Domain d1ldnc1: 1ldn C:15-162 [30168]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      4. 388247Domain d1ldnd1: 1ldn D:15-162 [30169]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      5. 388248Domain d1ldne1: 1ldn E:15-162 [30170]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      6. 388249Domain d1ldnf1: 1ldn F:15-162 [30171]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      7. 388250Domain d1ldng1: 1ldn G:15-162 [30172]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
      8. 388251Domain d1ldnh1: 1ldn H:15-162 [30173]
        Other proteins in same PDB: d1ldna2, d1ldnb2, d1ldnc2, d1ldnd2, d1ldne2, d1ldnf2, d1ldng2, d1ldnh2
        complexed with fbp, nad, oxm
    3. Domain for 2ldb:
  2. 388254Bifidobacterium longum, strain am101-2 [TaxId:216816] [51866] (2 PDB entries)
    1. Domains for 1lld:
      1. 388255Domain d1llda1: 1lld A:7-149 [30177]
        Other proteins in same PDB: d1llda2, d1lldb2
      2. 388256Domain d1lldb1: 1lld B:7-149 [30178]
        Other proteins in same PDB: d1llda2, d1lldb2
        complexed with nad; mutant
    2. Domains for 1lth:
      1. 388257Domain d1lthr1: 1lth R:7-149 [30179]
        Other proteins in same PDB: d1lthr2, d1ltht2
      2. 388258Domain d1ltht1: 1lth T:7-149 [30180]
        Other proteins in same PDB: d1lthr2, d1ltht2
        complexed with fbp, nad, oxm; mutant
  3. 388259Dogfish (Squalus acanthias) [TaxId:7797] [51862] (3 PDB entries)
    1. Domain for 1ldm:
    2. Domain for 6ldh:
    3. Domain for 8ldh:
  4. 388263Human (Homo sapiens), heart isoform (H chain) [TaxId:9606] [63939] (2 PDB entries)
    1. Domains for 1i0z:
      1. 388264Domain d1i0za1: 1i0z A:1-160 [61495]
        Other proteins in same PDB: d1i0za2, d1i0zb2
      2. 388265Domain d1i0zb1: 1i0z B:1-160 [61497]
        Other proteins in same PDB: d1i0za2, d1i0zb2
        complexed with nai, oxm
    2. Domains for 1t2f:
      1. 388266Domain d1t2fa1: 1t2f A:1-160 [99088]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      2. 388267Domain d1t2fb1: 1t2f B:1-160 [99090]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      3. 388268Domain d1t2fc1: 1t2f C:1-160 [99092]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
      4. 388269Domain d1t2fd1: 1t2f D:1-160 [99094]
        Other proteins in same PDB: d1t2fa2, d1t2fb2, d1t2fc2, d1t2fd2
        complexed with nad, oxq; mutant
  5. 388270Human (Homo sapiens), muscle isoform (M chain) [TaxId:9606] [63940] (1 PDB entry)
  6. 388279Lactobacillus casei [TaxId:1582] [51865] (1 PDB entry)
  7. 388281Lactobacillus pentosus [TaxId:1589] [69418] (1 PDB entry)
  8. 388286Malaria parasite (Plasmodium falciparum) [TaxId:5833] [51863] (9 PDB entries)
    1. Domain for 1ceq:
    2. Domain for 1cet:
    3. Domain for 1ldg:
    4. Domain for 1t24:
    5. Domain for 1t25:
    6. Domain for 1t26:
    7. Domain for 1t2c:
    8. Domain for 1t2d:
    9. Domain for 1t2e:
  9. 388296Mouse (Mus musculus) [TaxId:10090] [51861] (1 PDB entry)
  10. 388298Pig (Sus scrofa) [TaxId:9823] [51860] (3 PDB entries)
    1. Domain for 5ldh:
    2. Domains for 9ldb:
      1. 388301Domain d9ldba1: 9ldb A:1-162 [30156]
        Other proteins in same PDB: d9ldba2, d9ldbb2
      2. 388302Domain d9ldbb1: 9ldb B:1-162 [30157]
        Other proteins in same PDB: d9ldba2, d9ldbb2
        complexed with nad, oxm, so4
    3. Domains for 9ldt:
      1. 388299Domain d9ldta1: 9ldt A:1-162 [30154]
        Other proteins in same PDB: d9ldta2, d9ldtb2
      2. 388300Domain d9ldtb1: 9ldt B:1-162 [30155]
        Other proteins in same PDB: d9ldta2, d9ldtb2
        complexed with nad, oxm, so4
  11. 388304Plasmodium berghei [102165] (1 PDB entry)
  12. 388307Thermotoga maritima [TaxId:243274] [51867] (1 PDB entry)
  13. 388309Toxoplasma gondii [TaxId:5811] [102166] (4 PDB entries)
    1. Domain for 1pze:
    2. Domains for 1pzf:
      1. 388319Domain d1pzfa1: 1pzf A:14-163 [95417]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      2. 388320Domain d1pzfb1: 1pzf B:14-163 [95419]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      3. 388321Domain d1pzfc1: 1pzf C:14-163 [95421]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
      4. 388322Domain d1pzfd1: 1pzf D:14-163 [95423]
        Other proteins in same PDB: d1pzfa2, d1pzfb2, d1pzfc2, d1pzfd2
        complexed with a3d, oxl
    3. Domains for 1pzg:
      1. 388311Domain d1pzga1: 1pzg A:14-163 [95425]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      2. 388312Domain d1pzgb1: 1pzg B:14-163 [95427]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      3. 388313Domain d1pzgc1: 1pzg C:15-163 [95429]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
      4. 388314Domain d1pzgd1: 1pzg D:14-163 [95431]
        Other proteins in same PDB: d1pzga2, d1pzgb2, d1pzgc2, d1pzgd2
        complexed with a3d, so4
    4. Domains for 1pzh:
      1. 388315Domain d1pzha1: 1pzh A:14-163 [95433]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      2. 388316Domain d1pzhb1: 1pzh B:14-163 [95435]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      3. 388317Domain d1pzhc1: 1pzh C:14-163 [95437]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
      4. 388318Domain d1pzhd1: 1pzh D:14-163 [95439]
        Other proteins in same PDB: d1pzha2, d1pzhb2, d1pzhc2, d1pzhd2
        complexed with nad, oxl

More info for Protein Lactate dehydrogenase from c.2.1.5: LDH N-terminal domain-like

Timeline for Protein Lactate dehydrogenase from c.2.1.5: LDH N-terminal domain-like: