SCOP 1.73: Protein: Carbonyl reductase

Lineage for Protein: Carbonyl reductase

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Carbonyl reductase [51765] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [102144] (2 PDB entries)
dicarbonyl/L-xylulose reductase
1. Domains for 1pr9:
  1. Domain d1pr9a_: 1pr9 A: [95060]
  2. Domain d1pr9b_: 1pr9 B: [95061]
    complexed with 2hp, k, nap
2. Domains for 1wnt:
  1. Domain d1wnta1: 1wnt A:1-244 [121102]
    automatically matched to d1pr9a_
    complexed with nap
  2. Domain d1wntb1: 1wnt B:1-244 [121103]
    automatically matched to d1pr9a_
    complexed with nap
  3. Domain d1wntc1: 1wnt C:1-244 [121104]
    automatically matched to d1pr9a_
    complexed with nap
  4. Domain d1wntd1: 1wnt D:1-244 [121105]
    automatically matched to d1pr9a_
    complexed with nap
Mouse (Mus musculus) [TaxId:10090] [51766] (1 PDB entry)
- Domains for 1cyd:
  1. Domain d1cyda_: 1cyd A: [29825]
  2. Domain d1cydb_: 1cyd B: [29826]
  3. Domain d1cydc_: 1cyd C: [29827]
  4. Domain d1cydd_: 1cyd D: [29828]
    complexed with ipa, nap

More info for Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared (with stable ids) in SCOP 1.55
Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.71
Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.75
Protein Carbonyl reductase from c.2.1.2: Tyrosine-dependent oxidoreductases appears in the current release, SCOPe 2.08