SCOP 1.63: Species: Human (Homo sapiens), different isozymes

Lineage for Species: Human (Homo sapiens), different isozymes

Root: SCOP 1.63
Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)
Family c.2.1.1: Alcohol/glucose dehydrogenases, C-terminal domain [51736] (6 proteins)
N-terminal all-beta domain defines family
Protein Alcohol dehydrogenase [51737] (5 species)
Species Human (Homo sapiens), different isozymes [TaxId:9606] [51739] (17 PDB entries)

PDB entries in Species: Human (Homo sapiens), different isozymes:

Domain(s) for 1agn:
1. Domain d1agna2: 1agn A:175-324 [29753]
  Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
2. Domain d1agnb2: 1agn B:175-324 [29754]
  Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
3. Domain d1agnc2: 1agn C:175-324 [29755]
  Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
4. Domain d1agnd2: 1agn D:175-324 [29756]
  Other proteins in same PDB: d1agna1, d1agnb1, d1agnc1, d1agnd1
  sigma isozyme
  complexed with act, nad, zn
Domain(s) for 1d1s:
1. Domain d1d1sa2: 1d1s A:175-324 [29743]
  Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
2. Domain d1d1sb2: 1d1s B:175-324 [29744]
  Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
3. Domain d1d1sc2: 1d1s C:175-324 [29745]
  Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
4. Domain d1d1sd2: 1d1s D:175-324 [29746]
  Other proteins in same PDB: d1d1sa1, d1d1sb1, d1d1sc1, d1d1sd1
  sigma isozyme
  complexed with act, cac, nad, zn
Domain(s) for 1d1t:
1. Domain d1d1ta2: 1d1t A:175-324 [29735]
  Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
2. Domain d1d1tb2: 1d1t B:175-324 [29736]
  Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
3. Domain d1d1tc2: 1d1t C:175-324 [29737]
  Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
4. Domain d1d1td2: 1d1t D:175-324 [29738]
  Other proteins in same PDB: d1d1ta1, d1d1tb1, d1d1tc1, d1d1td1
  sigma isozyme
  complexed with act, cac, nad, zn; mutant
Domain(s) for 1deh:
1. Domain d1deha2: 1deh A:175-324 [29729]
  Other proteins in same PDB: d1deha1, d1dehb1
2. Domain d1dehb2: 1deh B:175-324 [29730]
  Other proteins in same PDB: d1deha1, d1dehb1
  complexed with cl, nad, pyz, zn
Domain(s) for 1hdx:
1. Domain d1hdxa2: 1hdx A:175-324 [29733]
  Other proteins in same PDB: d1hdxa1, d1hdxb1
2. Domain d1hdxb2: 1hdx B:175-324 [29734]
  Other proteins in same PDB: d1hdxa1, d1hdxb1
  complexed with cl, cxl, nad, zn
Domain(s) for 1hdy:
1. Domain d1hdya2: 1hdy A:175-324 [29739]
  Other proteins in same PDB: d1hdya1, d1hdyb1
2. Domain d1hdyb2: 1hdy B:175-324 [29740]
  Other proteins in same PDB: d1hdya1, d1hdyb1
  complexed with cl, nad, pyz, zn
Domain(s) for 1hdz:
1. Domain d1hdza2: 1hdz A:175-324 [29741]
  Other proteins in same PDB: d1hdza1, d1hdzb1
2. Domain d1hdzb2: 1hdz B:175-324 [29742]
  Other proteins in same PDB: d1hdza1, d1hdzb1
  complexed with cl, nad, zn; mutant
Domain(s) for 1hso:
1. Domain d1hsoa2: 1hso A:175-324 [29747]
  Other proteins in same PDB: d1hsoa1, d1hsob1
2. Domain d1hsob2: 1hso B:175-324 [29748]
  Other proteins in same PDB: d1hsoa1, d1hsob1
  alpha isozyme
  complexed with nad, pyz, zn
Domain(s) for 1hsz:
1. Domain d1hsza2: 1hsz A:175-324 [29727]
  Other proteins in same PDB: d1hsza1, d1hszb1
2. Domain d1hszb2: 1hsz B:175-324 [29728]
  Other proteins in same PDB: d1hsza1, d1hszb1
  beta-1 isozyme
  complexed with nad, po4, zn
Domain(s) for 1ht0:
1. Domain d1ht0a2: 1ht0 A:175-324 [29725]
  Other proteins in same PDB: d1ht0a1, d1ht0b1
2. Domain d1ht0b2: 1ht0 B:175-324 [29726]
  Other proteins in same PDB: d1ht0a1, d1ht0b1
  gamma-2 isozyme
  complexed with nad, zn; mutant
Domain(s) for 1htb:
1. Domain d1htba2: 1htb A:175-324 [29731]
  Other proteins in same PDB: d1htba1, d1htbb1
2. Domain d1htbb2: 1htb B:175-324 [29732]
  Other proteins in same PDB: d1htba1, d1htbb1
  complexed with cl, nad, pyz, zn
Domain(s) for 1m6h:
1. Domain d1m6ha2: 1m6h A:175-324 [74530]
  Other proteins in same PDB: d1m6ha1, d1m6hb1
2. Domain d1m6hb2: 1m6h B:175-324 [74532]
  Other proteins in same PDB: d1m6ha1, d1m6hb1
  glutathione-dependent formaldehyde dehydrogenase
  complexed with k, po4, zn
Domain(s) for 1m6w:
1. Domain d1m6wa2: 1m6w A:175-324 [74569]
  Other proteins in same PDB: d1m6wa1, d1m6wb1
2. Domain d1m6wb2: 1m6w B:175-324 [74571]
  Other proteins in same PDB: d1m6wa1, d1m6wb1
  glutathione-dependent formaldehyde dehydrogenase
  complexed with 12h, k, po4, zn
Domain(s) for 1ma0:
1. Domain d1ma0a2: 1ma0 A:175-324 [74606]
  Other proteins in same PDB: d1ma0a1, d1ma0b1
2. Domain d1ma0b2: 1ma0 B:175-324 [74608]
  Other proteins in same PDB: d1ma0a1, d1ma0b1
  glutathione-dependent formaldehyde dehydrogenase
  complexed with k, lau, nad, po4, zn
Domain(s) for 1mp0:
1. Domain d1mp0a2: 1mp0 A:175-324 [79371]
  Other proteins in same PDB: d1mp0a1, d1mp0b1
2. Domain d1mp0b2: 1mp0 B:175-324 [79373]
  Other proteins in same PDB: d1mp0a1, d1mp0b1
  glutathione-dependent formaldehyde dehydrogenase
  complexed with k, nad, po4, zn
Domain(s) for 1teh:
1. Domain d1teha2: 1teh A:175-324 [29749]
  Other proteins in same PDB: d1teha1, d1tehb1
2. Domain d1tehb2: 1teh B:175-324 [29750]
  Other proteins in same PDB: d1teha1, d1tehb1
  glutathione-dependent formaldehyde dehydrogenase
  complexed with nad, zn
Domain(s) for 3hud:
1. Domain d3huda2: 3hud A:175-324 [29751]
  Other proteins in same PDB: d3huda1, d3hudb1
2. Domain d3hudb2: 3hud B:175-324 [29752]
  Other proteins in same PDB: d3huda1, d3hudb1
  complexed with nad, zn

More info for Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase

Timeline for Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase:

Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase appears in SCOP 1.61
Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase appears in SCOP 1.65
Species Human (Homo sapiens), different isozymes [TaxId:9606] from c.2.1.1 Alcohol dehydrogenase appears in the current release, SCOPe 2.08