Lineage for Family c.1.23.1: Methylenetetrahydrofolate reductase

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2425802Superfamily c.1.23: FAD-linked oxidoreductase [51730] (3 families) (S)
    distinct cofactor-binding mode from both FMN- and NAD(P)-linked TIM-barrel oxidoreductases; families are related by a circular permutation
  5. 2425803Family c.1.23.1: Methylenetetrahydrofolate reductase [51731] (2 protein domains)
    automatically mapped to Pfam PF02219

Protein Domains:

  1. 2425804Methylenetetrahydrofolate reductase [51732] (2 species)
    1. 2425805Species Escherichia coli [TaxId:562] [51733] (7 PDB entries)
    2. 2425827Species Thermus thermophilus [TaxId:274] [102106] (1 PDB entry)
  2. 2425829automated matches [193645] (3 species)
    not a true protein
    1. 2425830Species Escherichia coli K-12 [TaxId:83333] [225710] (2 PDB entries)
    2. 2425837Species Haemophilus influenzae [TaxId:71421] [330195] (1 PDB entry)
    3. 2425844Species Thermus thermophilus HB8 [TaxId:300852] [193648] (2 PDB entries)

More info for Family c.1.23.1: Methylenetetrahydrofolate reductase

Timeline for Family c.1.23.1: Methylenetetrahydrofolate reductase: