SCOPe 2.06: Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

Lineage for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes [51703] (4 families)

Families:

1. c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain [51704] (2 proteins)
   the subunits are clearly related but only one (alpha) is active
   automatically mapped to Pfam PF01642

2. c.1.19.2: Glutamate mutase, large subunit [51707] (1 protein)
   automatically mapped to Pfam PF06368

3. c.1.19.3: Diol dehydratase, alpha subunit [51710] (2 proteins)
   automatically mapped to Pfam PF02286

4. c.1.19.4: D-lysine 5,6-aminomutase alpha subunit, KamD [117392] (1 protein)
   most similar to the glutamate mutase subunit; contains second cofactor, PLP
   automatically mapped to Pfam PF09043

More info for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

Timeline for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes:

• Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes first appeared (with stable ids) in SCOP 1.55
  
• Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes appears in SCOPe 2.05
  
• Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes appears in SCOPe 2.07
  
• Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes appears in the current release, SCOPe 2.08