Lineage for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 570217Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 573815Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes [51703] (4 families) (S)

Families:

  1. 573816c.1.19.1: Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain [51704] (2 proteins)
    the subunits are clearly related but only one (alpha) is active
  2. 573851c.1.19.2: Glutamate mutase, large subunit [51707] (1 protein)
  3. 573860c.1.19.3: Diol dehydratase, alpha subunit [51710] (1 protein)
  4. 573882c.1.19.4: D-lysine 5,6-aminomutase alpha subunit, KamD [117392] (1 protein)
    most similar to the glutamate mutase subunit; contains second cofactor, PLP

More info for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes

Timeline for Superfamily c.1.19: Cobalamin (vitamin B12)-dependent enzymes: