Lineage for Protein: Isocitrate lyase

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 570217Fold c.1: TIM beta/alpha-barrel [51350] (32 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 573147Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (6 families) (S)
  5. 573273Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (3 proteins)
    forms a swapped dimer
  6. 573289Protein Isocitrate lyase [51642] (3 species)
    elaborated with additional subdomains

Species:

  1. 573290Aspergillus nidulans [TaxId:162425] [51643] (1 PDB entry)
  2. 573292Escherichia coli [TaxId:562] [63923] (1 PDB entry)
  3. 573297Mycobacterium tuberculosis [TaxId:1773] [51644] (3 PDB entries)
    1. Domains for 1f61:
      1. 573302Domain d1f61a_: 1f61 A: [29319]
      2. 573303Domain d1f61b_: 1f61 B: [29320]
        complexed with mg
    2. Domains for 1f8i:
      1. 573304Domain d1f8ia_: 1f8i A: [29321]
      2. 573305Domain d1f8ib_: 1f8i B: [29322]
      3. 573306Domain d1f8ic_: 1f8i C: [29323]
      4. 573307Domain d1f8id_: 1f8i D: [29324]
        complexed with glv, mg, sin; mutant
    3. Domains for 1f8m:
      1. 573298Domain d1f8ma_: 1f8m A: [29315]
      2. 573299Domain d1f8mb_: 1f8m B: [29316]
      3. 573300Domain d1f8mc_: 1f8m C: [29317]
      4. 573301Domain d1f8md_: 1f8m D: [29318]
        complexed with mg, pyr

More info for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like

Timeline for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like: