SCOP 1.75: Protein: Enolase

Lineage for Protein: Enolase

Root: SCOP 1.75
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.11: Enolase C-terminal domain-like [51604] (2 families)

(S)

binds metal ion (magnesium or manganese) in conserved site inside barrel
N-terminal alpha+beta domain is common to this superfamily

Family c.1.11.1: Enolase [51605] (1 protein)
Protein Enolase [51606] (8 species)
Fold of this protein slightly differs from common fold in topology

Species:

Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [51607] (16 PDB entries)
1. Domains for 1ebg:
  1. Domain d1ebga1: 1ebg A:142-436 [29209]
    Other proteins in same PDB: d1ebga2, d1ebgb2
  2. Domain d1ebgb1: 1ebg B:142-436 [29210]
    Other proteins in same PDB: d1ebga2, d1ebgb2
    complexed with mg, pah
2. Domains for 1ebh:
  1. Domain d1ebha1: 1ebh A:142-436 [29205]
    Other proteins in same PDB: d1ebha2, d1ebhb2
  2. Domain d1ebhb1: 1ebh B:142-436 [29206]
    Other proteins in same PDB: d1ebha2, d1ebhb2
    complexed with cl, mg
3. Domain for 1els:
  - Domain d1elsa1: 1els A:142-436 [29213]
    Other proteins in same PDB: d1elsa2
    complexed with mn, pah
4. Domains for 1l8p:
  1. Domain d1l8pa1: 1l8p A:142-436 [73692]
    Other proteins in same PDB: d1l8pa2, d1l8pb2, d1l8pc2, d1l8pd2
  2. Domain d1l8pb1: 1l8p B:642-936 [73694]
    Other proteins in same PDB: d1l8pa2, d1l8pb2, d1l8pc2, d1l8pd2
  3. Domain d1l8pc1: 1l8p C:1142-1436 [73696]
    Other proteins in same PDB: d1l8pa2, d1l8pb2, d1l8pc2, d1l8pd2
  4. Domain d1l8pd1: 1l8p D:1642-1936 [73698]
    Other proteins in same PDB: d1l8pa2, d1l8pb2, d1l8pc2, d1l8pd2
    complexed with mg, pah; mutant
5. Domain for 1nel:
  - Domain d1nela1: 1nel A:142-436 [29214]
    Other proteins in same PDB: d1nela2
    complexed with f f, mg, po4
6. Domains for 1one:
  1. Domain d1onea1: 1one A:142-436 [29200]
    Other proteins in same PDB: d1onea2, d1oneb2
  2. Domain d1oneb1: 1one B:142-436 [29201]
    Other proteins in same PDB: d1onea2, d1oneb2
    complexed with mg, pag, pep
7. Domains for 1p43:
  1. Domain d1p43a1: 1p43 A:142-436 [94072]
    Other proteins in same PDB: d1p43a2, d1p43b2
  2. Domain d1p43b1: 1p43 B:642-936 [94074]
    Other proteins in same PDB: d1p43a2, d1p43b2
    complexed with mg, pag; mutant
8. Domains for 1p48:
  1. Domain d1p48a1: 1p48 A:142-436 [94085]
    Other proteins in same PDB: d1p48a2, d1p48b2
  2. Domain d1p48b1: 1p48 B:642-936 [94087]
    Other proteins in same PDB: d1p48a2, d1p48b2
    complexed with mg, pep; mutant
9. Domains for 2al1:
  1. Domain d2al1a1: 2al1 A:142-436 [126949]
    Other proteins in same PDB: d2al1a2, d2al1b2
    automatically matched to d1ebga1
    complexed with 2pg, cl, k, mg, pep
  2. Domain d2al1b1: 2al1 B:142-436 [126951]
    Other proteins in same PDB: d2al1a2, d2al1b2
    automatically matched to d1ebga1
    complexed with 2pg, cl, k, mg, pep
10. Domains for 2al2:
  1. Domain d2al2a1: 2al2 A:142-436 [126953]
    Other proteins in same PDB: d2al2a2, d2al2b2
    automatically matched to d1ebga1
    complexed with 2pg, cl, k, mg, pep
  2. Domain d2al2b1: 2al2 B:142-436 [126955]
    Other proteins in same PDB: d2al2a2, d2al2b2
    automatically matched to d1ebga1
    complexed with 2pg, cl, k, mg, pep
11. Domains for 2one:
  1. Domain d2onea1: 2one A:142-436 [29203]
    Other proteins in same PDB: d2onea2, d2oneb2
  2. Domain d2oneb1: 2one B:142-436 [29204]
    Other proteins in same PDB: d2onea2, d2oneb2
    complexed with li, mg, pag, pep
12. Domain for 3enl:
  - Domain d3enla1: 3enl A:142-436 [29211]
    Other proteins in same PDB: d3enla2
    complexed with so4
13. Domain for 4enl:
  - Domain d4enla1: 4enl A:142-436 [29202]
    Other proteins in same PDB: d4enla2
    complexed with so4, zn
14. Domain for 5enl:
  - Domain d5enla1: 5enl A:142-436 [29207]
    Other proteins in same PDB: d5enla2
    complexed with 2pg, ca
15. Domain for 6enl:
  - Domain d6enla1: 6enl A:142-436 [29208]
    Other proteins in same PDB: d6enla2
    complexed with 2pl, zn
16. Domain for 7enl:
  - Domain d7enla1: 7enl A:142-436 [29212]
    Other proteins in same PDB: d7enla2
    complexed with 2pg, mg
Enterococcus hirae [TaxId:1354] [89498] (1 PDB entry)
- Domains for 1iyx:
  1. Domain d1iyxa1: 1iyx A:137-431 [83815]
    Other proteins in same PDB: d1iyxa2, d1iyxb2
  2. Domain d1iyxb1: 1iyx B:137-431 [83817]
    Other proteins in same PDB: d1iyxa2, d1iyxb2
    complexed with cry, mg, so4
Escherichia coli [TaxId:562] [69396] (2 PDB entries)
1. Domains for 1e9i:
  1. Domain d1e9ia1: 1e9i A:140-430 [64818]
    Other proteins in same PDB: d1e9ia2, d1e9ib2, d1e9ic2, d1e9id2
    CASP4
  2. Domain d1e9ib1: 1e9i B:140-430 [64820]
    Other proteins in same PDB: d1e9ia2, d1e9ib2, d1e9ic2, d1e9id2
    CASP4
  3. Domain d1e9ic1: 1e9i C:140-428 [64822]
    Other proteins in same PDB: d1e9ia2, d1e9ib2, d1e9ic2, d1e9id2
    CASP4
  4. Domain d1e9id1: 1e9i D:140-431 [64824]
    Other proteins in same PDB: d1e9ia2, d1e9ib2, d1e9ic2, d1e9id2
    CASP4
    complexed with mg, so4
2. Domains for 2fym:
  1. Domain d2fyma1: 2fym A:140-431 [134379]
    Other proteins in same PDB: d2fyma2, d2fymc2, d2fymd2, d2fymf2
    automatically matched to d1e9id1
    complexed with mg
  2. Domain d2fymc1: 2fym C:140-430 [134381]
    Other proteins in same PDB: d2fyma2, d2fymc2, d2fymd2, d2fymf2
    automatically matched to d1e9id1
    complexed with mg
  3. Domain d2fymd1: 2fym D:140-430 [134383]
    Other proteins in same PDB: d2fyma2, d2fymc2, d2fymd2, d2fymf2
    automatically matched to d1e9id1
    complexed with mg
  4. Domain d2fymf1: 2fym F:140-431 [134385]
    Other proteins in same PDB: d2fyma2, d2fymc2, d2fymd2, d2fymf2
    automatically matched to d1e9id1
    complexed with mg
European lobster (Homarus vulgaris) [TaxId:6707] [51608] (2 PDB entries)
1. Domain for 1pdy:
  - Domain d1pdya1: 1pdy A:140-433 [29216]
    Other proteins in same PDB: d1pdya2
    complexed with so4
2. Domain for 1pdz:
  - Domain d1pdza1: 1pdz A:140-433 [29215]
    Other proteins in same PDB: d1pdza2
    complexed with mn, pga
Human (Homo sapiens), gamma isoform [TaxId:9606] [110371] (3 PDB entries)
Uniprot P09104
1. Domains for 1te6:
  1. Domain d1te6a1: 1te6 A:140-433 [106797]
    Other proteins in same PDB: d1te6a2, d1te6b2
  2. Domain d1te6b1: 1te6 B:140-433 [106799]
    Other proteins in same PDB: d1te6a2, d1te6b2
    complexed with cl, mg, po4, trs
2. Domains for 2akm:
  1. Domain d2akma1: 2akm A:140-433 [126919]
    Other proteins in same PDB: d2akma2, d2akmb2
    automatically matched to d1te6a1
    complexed with mg, po4, trs
  2. Domain d2akmb1: 2akm B:140-432 [126921]
    Other proteins in same PDB: d2akma2, d2akmb2
    automatically matched to d1te6a1
    complexed with mg, po4, trs
3. Domains for 2akz:
  1. Domain d2akza1: 2akz A:140-433 [126944]
    Other proteins in same PDB: d2akza2, d2akzb2
    automatically matched to d1te6a1
    complexed with f, mg, po4, trs
  2. Domain d2akzb1: 2akz B:1140-1432 [126946]
    Other proteins in same PDB: d2akza2, d2akzb2
    automatically matched to d1te6a1
    complexed with f, mg, po4, trs
Streptococcus pneumoniae [TaxId:1313] [141843] (1 PDB entry)
Uniprot Q8DPS0 138-433
- Domains for 1w6t:
  1. Domain d1w6ta1: 1w6t A:138-433 [120670]
    Other proteins in same PDB: d1w6ta2, d1w6tb2
    complexed with 2pe, mg
  2. Domain d1w6tb1: 1w6t B:138-433 [120672]
    Other proteins in same PDB: d1w6ta2, d1w6tb2
    automatically matched to 1W6T A:138-433
    complexed with 2pe, mg
Trypanosoma brucei brucei [TaxId:5702] [89497] (1 PDB entry)
- Domain for 1oep:
  - Domain d1oepa1: 1oep A:139-429 [86918]
    Other proteins in same PDB: d1oepa2
    complexed with edo, so4, zn
Trypanosoma brucei [TaxId:5691] [159415] (6 PDB entries)
1. Domain for 2ptw:
  - Domain d2ptwa1: 2ptw A:139-429 [149838]
    Other proteins in same PDB: d2ptwa2
    automatically matched to d1oepa1
    complexed with edo, so4, zn; mutant
2. Domain for 2ptx:
  - Domain d2ptxa1: 2ptx A:139-429 [149840]
    Other proteins in same PDB: d2ptxa2
    automatically matched to d1oepa1
    complexed with edo, so4, zn; mutant
3. Domain for 2pty:
  - Domain d2ptya1: 2pty A:139-429 [149842]
    Other proteins in same PDB: d2ptya2
    automatically matched to d1oepa1
    complexed with edo, pep, zn; mutant
4. Domain for 2ptz:
  - Domain d2ptza1: 2ptz A:139-429 [149844]
    Other proteins in same PDB: d2ptza2
    automatically matched to d1oepa1
    complexed with edo, pah, zn; mutant
5. Domain for 2pu0:
  - Domain d2pu0a1: 2pu0 A:139-429 [149846]
    Other proteins in same PDB: d2pu0a2
    automatically matched to d1oepa1
    complexed with edo, pah, zn; mutant
6. Domain for 2pu1:
  - Domain d2pu1a1: 2pu1 A:139-429 [149848]
    Other proteins in same PDB: d2pu1a2
    automatically matched to d1oepa1
    complexed with edo, fsg, zn; mutant

More info for Protein Enolase from c.1.11.1: Enolase

Timeline for Protein Enolase from c.1.11.1: Enolase:

Protein Enolase from c.1.11.1: Enolase first appeared (with stable ids) in SCOP 1.55
Protein Enolase from c.1.11.1: Enolase appears in SCOP 1.73
Protein Enolase from c.1.11.1: Enolase appears in SCOPe 2.01
Protein Enolase from c.1.11.1: Enolase appears in the current release, SCOPe 2.08