SCOPe 2.08: Protein: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)

Lineage for Protein: 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.10: Aldolase [51569] (9 families)
Common fold covers whole protein structure
Family c.1.10.4: Class I DAHP synthetase [51599] (3 proteins)
Protein 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) [51600] (3 species)

Species:

Baker's yeast (Saccharomyces cerevisiae), tyrosine-regulated isozyme [TaxId:4932] [82272] (11 PDB entries)
1. Domains for 1hfb:
  1. Domain d1hfba_: 1hfb A: [76706]
    complexed with pep
  2. Domain d1hfbb_: 1hfb B: [76707]
    complexed with pep
  3. Domain d1hfbc_: 1hfb C: [76708]
    complexed with pep
  4. Domain d1hfbd_: 1hfb D: [76709]
    complexed with pep
  5. Domain d1hfbe_: 1hfb E: [76710]
    complexed with pep
  6. Domain d1hfbf_: 1hfb F: [76711]
    complexed with pep
  7. Domain d1hfbg_: 1hfb G: [76712]
    complexed with pep
  8. Domain d1hfbh_: 1hfb H: [76713]
    complexed with pep
2. Domains for 1oab:
  1. Domain d1oaba_: 1oab A: [92702]
    complexed with mn, pep
  2. Domain d1oabb_: 1oab B: [92703]
    complexed with mn, pep
3. Domains for 1of6:
  1. Domain d1of6a_: 1of6 A: [92811]
    complexed with dty, mn
  2. Domain d1of6b_: 1of6 B: [92812]
    complexed with dty, mn
  3. Domain d1of6c_: 1of6 C: [92813]
    complexed with dty, mn
  4. Domain d1of6d_: 1of6 D: [92814]
    complexed with dty, mn
  5. Domain d1of6e_: 1of6 E: [92815]
    complexed with dty, mn
  6. Domain d1of6f_: 1of6 F: [92816]
    complexed with dty, mn
  7. Domain d1of6g_: 1of6 G: [92817]
    complexed with dty, mn
  8. Domain d1of6h_: 1of6 H: [92818]
    complexed with dty, mn
4. Domains for 1of8:
  1. Domain d1of8a_: 1of8 A: [92819]
    complexed with co, g3p, gol, pep
  2. Domain d1of8b_: 1of8 B: [92820]
    complexed with co, g3p, gol, pep
5. Domains for 1ofa:
  1. Domain d1ofaa_: 1ofa A: [92822]
    complexed with co, gol, pep
  2. Domain d1ofab_: 1ofa B: [92823]
    complexed with co, gol, pep
6. Domains for 1ofb:
  1. Domain d1ofba_: 1ofb A: [92824]
    complexed with gol, mn
  2. Domain d1ofbb_: 1ofb B: [92825]
    complexed with gol, mn
7. Domains for 1ofo:
  1. Domain d1ofoa_: 1ofo A: [92832]
    complexed with pga
  2. Domain d1ofob_: 1ofo B: [92833]
    complexed with pga
8. Domains for 1ofp:
  1. Domain d1ofpa_: 1ofp A: [92834]
  2. Domain d1ofpb_: 1ofp B: [92835]
  3. Domain d1ofpc_: 1ofp C: [92836]
  4. Domain d1ofpd_: 1ofp D: [92837]
9. Domains for 1ofq:
  1. Domain d1ofqa_: 1ofq A: [92838]
    complexed with mn
  2. Domain d1ofqb_: 1ofq B: [92839]
    complexed with mn
  3. Domain d1ofqc_: 1ofq C: [92840]
    complexed with mn
  4. Domain d1ofqd_: 1ofq D: [92841]
    complexed with mn
10. Domains for 1ofr:
  1. Domain d1ofra_: 1ofr A: [92842]
    complexed with mn, phe
  2. Domain d1ofrb_: 1ofr B: [92843]
    complexed with mn, phe
  3. Domain d1ofrc_: 1ofr C: [92844]
    complexed with mn, phe
  4. Domain d1ofrd_: 1ofr D: [92845]
    complexed with mn, phe
  5. Domain d1ofre_: 1ofr E: [92846]
    complexed with mn, phe
  6. Domain d1ofrf_: 1ofr F: [92847]
    complexed with mn, phe
  7. Domain d1ofrg_: 1ofr G: [92848]
    complexed with mn, phe
  8. Domain d1ofrh_: 1ofr H: [92849]
    complexed with mn, phe
11. Domains for 1og0:
  1. Domain d1og0a_: 1og0 A: [92854]
    complexed with mn, phe; mutant
  2. Domain d1og0b_: 1og0 B: [92855]
    complexed with mn, phe; mutant
  3. Domain d1og0c_: 1og0 C: [92856]
    complexed with mn, phe; mutant
  4. Domain d1og0d_: 1og0 D: [92857]
    complexed with mn, phe; mutant
  5. Domain d1og0e_: 1og0 E: [92858]
    complexed with mn, phe; mutant
  6. Domain d1og0f_: 1og0 F: [92859]
    complexed with mn, phe; mutant
  7. Domain d1og0g_: 1og0 G: [92860]
    complexed with mn, phe; mutant
  8. Domain d1og0h_: 1og0 H: [92861]
    complexed with mn, phe; mutant
Escherichia coli, phenylalanine-regulated isozyme [TaxId:562] [51601] (4 PDB entries)
1. Domains for 1gg1:
  1. Domain d1gg1a_: 1gg1 A: [29187]
    complexed with mn, pga, so4
  2. Domain d1gg1b_: 1gg1 B: [29188]
    complexed with mn, pga, so4
  3. Domain d1gg1c_: 1gg1 C: [29189]
    complexed with mn, pga, so4
  4. Domain d1gg1d_: 1gg1 D: [29190]
    complexed with mn, pga, so4
2. Domains for 1kfl:
  1. Domain d1kfla1: 1kfl A:2-350 [72413]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  2. Domain d1kflb1: 1kfl B:2-350 [72414]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  3. Domain d1kflc1: 1kfl C:2-350 [72415]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  4. Domain d1kfld1: 1kfl D:2-350 [72416]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  5. Domain d1kfle1: 1kfl E:2-350 [72417]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  6. Domain d1kflf1: 1kfl F:2-350 [72418]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  7. Domain d1kflg1: 1kfl G:2-350 [72419]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
  8. Domain d1kflh1: 1kfl H:2-350 [72420]
    Other proteins in same PDB: d1kfla2, d1kflb2, d1kflc2, d1kfld2, d1kfle2, d1kflf2, d1kflg2, d1kflh2
    complexed with mn, pep, phe, so4
3. Domains for 1n8f:
  1. Domain d1n8fa_: 1n8f A: [85397]
    complexed with mn, pep, so4; mutant
  2. Domain d1n8fb_: 1n8f B: [85398]
    complexed with mn, pep, so4; mutant
  3. Domain d1n8fc_: 1n8f C: [85399]
    complexed with mn, pep, so4; mutant
  4. Domain d1n8fd_: 1n8f D: [85400]
    complexed with mn, pep, so4; mutant
4. Domains for 1qr7:
  1. Domain d1qr7a_: 1qr7 A: [29191]
    complexed with pb, pep, so4
  2. Domain d1qr7b_: 1qr7 B: [29192]
    complexed with pb, pep, so4
  3. Domain d1qr7c_: 1qr7 C: [29193]
    complexed with pb, pep, so4
  4. Domain d1qr7d_: 1qr7 D: [29194]
    complexed with pb, pep, so4
Thermotoga maritima [TaxId:2336] [110363] (1 PDB entry)
Uniprot Q9WYH8
- Domains for 1rzm:
  1. Domain d1rzma_: 1rzm A: [105137]
    complexed with cd, e4p, pep
  2. Domain d1rzmb_: 1rzm B: [105138]
    complexed with cd, e4p, pep

More info for Protein 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) from c.1.10.4: Class I DAHP synthetase

Timeline for Protein 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) from c.1.10.4: Class I DAHP synthetase:

Protein 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) from c.1.10.4: Class I DAHP synthetase first appeared (with stable ids) in SCOP 1.55
Protein 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG) from c.1.10.4: Class I DAHP synthetase appears in SCOPe 2.07