Lineage for Superfamily c.1.10: Aldolase

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 305036Fold c.1: TIM beta/alpha-barrel [51350] (26 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 306689Superfamily c.1.10: Aldolase [51569] (5 families) (S)
    Common fold covers whole protein structure

Families:

  1. 306690c.1.10.1: Class I aldolase [51570] (8 proteins)
    the catalytic lysine forms schiff-base intermediate with substrate
    possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels
  2. 306884c.1.10.2: Class II FBP aldolase [51591] (2 proteins)
    metal-dependent
  3. 306897c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (1 protein)
    hybrid of classes I and II aldolase
  4. 306927c.1.10.4: Class I DAHP synthetase [51599] (2 proteins)
  5. 306995c.1.10.5: 4-hydroxy-2-oxovalerate aldolase DmpG, catalytic domain [89494] (1 protein)

More info for Superfamily c.1.10: Aldolase

Timeline for Superfamily c.1.10: Aldolase: