Lineage for Superfamily c.1.9: Metallo-dependent hydrolases

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 681098Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 683612Superfamily c.1.9: Metallo-dependent hydrolases [51556] (15 families) (S)
    the beta-sheet barrel is similarly distorted and capped by a C-terminal helix
    has transition metal ions bound inside the barrel

Families:

  1. 683613c.1.9.1: Adenosine/AMP deaminase [51557] (2 proteins)
  2. 683659c.1.9.2: alpha-subunit of urease, catalytic domain [51560] (1 protein)
  3. 683699c.1.9.3: Phosphotriesterase-like [51564] (2 proteins)
  4. 683733c.1.9.4: Dihydroorotase [63917] (1 protein)
  5. 683740c.1.9.5: Cytosine deaminase catalytic domain [69390] (1 protein)
  6. 683751c.1.9.6: Hydantoinase (dihydropyrimidinase), catalytic domain [75073] (5 proteins)
  7. 683812c.1.9.7: Renal dipeptidase [75079] (1 protein)
  8. 683819c.1.9.8: Uronate isomerase TM0064 [75082] (1 protein)
    contains all-alpha subdomain inserted after the first strand
  9. 683825c.1.9.9: Hypothetical protein TM0936, probable catalytic domain [82258] (1 protein)
  10. 683830c.1.9.10: N-acetylglucosamine-6-phosphate deacetylase, NagA, catalytic domain [82261] (1 protein)
  11. 683843c.1.9.11: D-aminoacylase, catalytic domain [82264] (1 protein)
  12. 683854c.1.9.12: TatD Mg-dependent DNase-like [82267] (4 proteins)
  13. 683868c.1.9.13: Isoaspartyl dipeptidase, catalytic domain [89489] (1 protein)
  14. 683881c.1.9.14: Adenine deaminase-like [141816] (1 protein)
  15. 683885c.1.9.15: PP1699/LP2961-like [141819] (5 proteins)
    Pfam PF04909; Amidohydrolase; stand-alone domain

More info for Superfamily c.1.9: Metallo-dependent hydrolases

Timeline for Superfamily c.1.9: Metallo-dependent hydrolases: