SCOP 1.69: Superfamily c.1.8: (Trans)glycosidases

Lineage for Superfamily c.1.8: (Trans)glycosidases

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (11 families)

Families:

1. c.1.8.1: Amylase, catalytic domain [51446] (24 proteins)
   members of the family may contain various insert subdomains
   in alpha-amylases and closer relatives this domain is usually followed by a common all-beta domain

2. c.1.8.3: beta-glycanases [51487] (22 proteins)
   consist of a number of sequence families

3. c.1.8.4: Family 1 of glycosyl hydrolase [51521] (4 proteins)

4. c.1.8.5: Type II chitinase [51534] (14 proteins)
   glycosylase family 18

5. c.1.8.6: beta-N-acetylhexosaminidase catalytic domain [51550] (3 proteins)
   Glycosyl hydrolase family 20, GH20

6. c.1.8.7: Beta-D-glucan exohydrolase, N-terminal domain [51553] (1 protein)

7. c.1.8.8: 1,4-beta-N-acetylmuraminidase [63912] (3 proteins)
   Glycosyl hydrolase family 25; probably have evolved from a type II chitinase ancestor
   permutation of the common fold; strand 8 is antiparallel to the rest of the barrel

8. c.1.8.9: Bee venom hyaluronidase [69387] (1 protein)
   distorted barrel lacks the second strand

9. c.1.8.10: alpha-D-glucuronidase catalytic domain [82253] (1 protein)
   Glycosyl hydrolase family 67, GH67; structurally related to GH20; contains extra C-terminal alpha-helical subdomain

10. c.1.8.11: Putative alpha-L-fucosidase, catalytic domain [102079] (1 protein)
    glycosyl hydrolase family 29; contains additional beta-barrel with a topological similarity to the C-terminal domain of alpha amylases

11. c.1.8.12: Outer surface protein, N-terminal domain [110354] (1 protein)
    corresponds to the N-terminal part of Pfam 05913

More info for Superfamily c.1.8: (Trans)glycosidases

Timeline for Superfamily c.1.8: (Trans)glycosidases:

• Superfamily c.1.8: (Trans)glycosidases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily c.1.8: (Trans)glycosidases appears in SCOP 1.67
  
• Superfamily c.1.8: (Trans)glycosidases appears in SCOP 1.71
  
• Superfamily c.1.8: (Trans)glycosidases appears in the current release, SCOPe 2.08