Lineage for Family b.85.4.1: dUTPase-like

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 811032Fold b.85: beta-clip [51268] (7 superfamilies)
    double-stranded ribbon sharply bent in two places; the ribbon ends form incomplete barrel; jelly-roll
  4. 811150Superfamily b.85.4: dUTPase-like [51283] (1 family) (S)
    forms tight trimer through an additional beta-sheet in each subunit
    subunit beta-sheets are orthogonally packed around the three-fold axis
  5. 811151Family b.85.4.1: dUTPase-like [51284] (4 proteins)

Proteins:

  1. 811152Bifunctional dCTP deaminase/dUTPase [89425] (1 species)
    elaborated fold with additional structures
  2. 811163Deoxycytidine triphosphate deaminase (dCTP deaminase) [117335] (1 species)
  3. 811183Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) [51285] (6 species)
    1. 811184Species Equine infectious anemia virus [TaxId:11665] [51288] (2 PDB entries)
    2. 811187Species Escherichia coli [TaxId:562] [51286] (10 PDB entries)
      Uniprot P06968
    3. 811198Species Feline immunodeficiency virus [TaxId:11673] [51287] (8 PDB entries)
    4. 811217Species Human (Homo sapiens) [TaxId:9606] [102010] (4 PDB entries)
    5. 811233Species Mycobacterium tuberculosis, rv2697c [TaxId:1773] [82213] (8 PDB entries)
    6. 811252Species Plasmodium falciparum [TaxId:5833] [141654] (1 PDB entry)
      Uniprot Q8II92 1-159
  4. 811256Monomeric viral dUTPase [141655] (1 species)
    related to the trimeric dUTPase domain by domain duplication, fusion and partial deletion; retains only one of the three ancestral active sites

More info for Family b.85.4.1: dUTPase-like

Timeline for Family b.85.4.1: dUTPase-like: