SCOP 1.63: Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Lineage for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

1. Root: SCOP 1.63

2. Class b: All beta proteins [48724] (119 folds)

3. Fold b.55: PH domain-like [50728] (1 superfamily)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (6 families)

5. Family b.55.1.2: Phosphotyrosine-binding domain (PTB) [50755] (4 proteins)

Proteins:

1. Insulin receptor substrate 1, IRS-1 [50758] (1 species)
   duplication: contains two domains of this fold

   • Species Human (Homo sapiens) [TaxId:9606] [50759] (2 PDB entries)

2. Numb [50762] (1 species)

   • Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [50763] (2 PDB entries)

3. Shc adaptor protein [50760] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50761] (1 PDB entry)

4. X11 [50756] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50757] (2 PDB entries)

More info for Family b.55.1.2: Phosphotyrosine-binding domain (PTB)

Timeline for Family b.55.1.2: Phosphotyrosine-binding domain (PTB):

• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) first appeared (with stable ids) in SCOP 1.55
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in SCOP 1.61
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in SCOP 1.65
  
• Family b.55.1.2: Phosphotyrosine-binding domain (PTB) appears in the current release, SCOPe 2.08