Class b: All beta proteins [48724] (149 folds) |
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily) barrel, closed; n=6, S=8; greek-key duplication: consists of two domains of the same fold |
Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families) |
Family b.47.1.3: Viral proteases [50596] (4 proteins) beta sheet in the first domain is opened rather than forms a barrel |
Protein NS3 protease [50600] (2 species) |
Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (14 PDB entries) |
Domain d1a1qa_: 1a1q A: [26414] |
Domain d1a1qb_: 1a1q B: [26415] |
Domain d1a1qc_: 1a1q C: [26416] complexed with zn |
Domain d1a1r.1: 1a1r A:,C: [26406] |
Domain d1a1r.2: 1a1r B:,D: [26407] complexed with zn; mutant |
Domain d1bt7__: 1bt7 - [26418] complexed with zn; mutant |
Domain d1cu1a1: 1cu1 A:705-720,A:3-186 [26408] Other proteins in same PDB: d1cu1a2, d1cu1a3, d1cu1b2, d1cu1b3 |
Domain d1cu1b1: 1cu1 B:1705-1720,B:1003-1186 [26409] Other proteins in same PDB: d1cu1a2, d1cu1a3, d1cu1b2, d1cu1b3 complexed with po4, zn |
Domain d1dxp.1: 1dxp A:,C: [26404] |
Domain d1dxp.2: 1dxp B:,D: [26405] complexed with gol, zn |
Domain d1dxwa_: 1dxw A: [26417] complexed with abk, zn; mutant |
Domain d1dy8.1: 1dy8 A:,C: [26410] |
Domain d1dy8.2: 1dy8 B:,D: [26411] complexed with cbz, fki |
Domain d1dy9.1: 1dy9 A:,C: [26400] |
Domain d1dy9.2: 1dy9 B:,D: [26401] complexed with boc, fki, zn |
Domain d1jxp.1: 1jxp A:,C: [26402] |
Domain d1jxp.2: 1jxp B:,D: [26403] complexed with zn |
Domain d1n1l.1: 1n1l A:,C: [91544] |
Domain d1n1l.2: 1n1l B:,D: [91545] complexed with trl, zn; mutant |
Domain d1ns3.1: 1ns3 A:,C: [26412] |
Domain d1ns3.2: 1ns3 B:,D: [26413] complexed with zn; mutant |
Domain d1rgq.1: 1rgq A:,D: [111803] |
Domain d1rgq.2: 1rgq B:,C: [111804] complexed with akp, zn |
Domain d1rtl.1: 1rtl A:,C: [111934] |
Domain d1rtlb_: 1rtl B: [111935] |
Domain d1rtld_: 1rtl D: [111936] complexed with cpx, zn |
Domain d1w3c.1: 1w3c A:,C: [114138] |
Domain d1w3c.2: 1w3c B:,D: [114139] complexed with dn1, dn2; mutant |
Timeline for Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] from b.47.1.3 NS3 protease: