SCOPe 2.08: Protein: Coagulation factor Xa, protease domain

Lineage for Protein: Coagulation factor Xa, protease domain

Root: SCOPe 2.08
Class b: All beta proteins [48724] (180 folds)
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
barrel, closed; n=6, S=8; greek-key
duplication: consists of two domains of the same fold
Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)
Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
Protein Coagulation factor Xa, protease domain [50574] (2 species)

Species:

Cow (Bos taurus) [TaxId:9913] [50576] (1 PDB entry)
- Domain for 1kig:
  - Domain d1kigh_: 1kig H: [26346]
    Other proteins in same PDB: d1kigi_, d1kigl_
Human (Homo sapiens) [TaxId:9606] [50575] (58 PDB entries)
Uniprot P00742 235-467
1. Domain for 1c5m:
  - Domain d1c5md_: 1c5m D: [26338]
    Other proteins in same PDB: d1c5mf_
2. Domain for 1ezq:
  - Domain d1ezqa_: 1ezq A: [26340]
    Other proteins in same PDB: d1ezqb_
    complexed with ca, rpr
3. Domain for 1f0r:
  - Domain d1f0ra_: 1f0r A: [26337]
    Other proteins in same PDB: d1f0rb_
    complexed with 815, ca
4. Domain for 1f0s:
  - Domain d1f0sa_: 1f0s A: [26339]
    Other proteins in same PDB: d1f0sb_
    complexed with ca, pr2
5. Domain for 1fax:
  - Domain d1faxa_: 1fax A: [26345]
    Other proteins in same PDB: d1faxl_
    complexed with ca, dx9
6. Domain for 1fjs:
  - Domain d1fjsa_: 1fjs A: [26336]
    Other proteins in same PDB: d1fjsl_
    complexed with ca, cl, gol, z34
7. Domain for 1g2l:
  - Domain d1g2la_: 1g2l A: [65112]
    Other proteins in same PDB: d1g2lb_
    complexed with ca, t87
8. Domain for 1g2m:
  - Domain d1g2ma_: 1g2m A: [65114]
    Other proteins in same PDB: d1g2mb_
    complexed with ca, r11
9. Domain for 1hcg:
  - Domain d1hcga_: 1hcg A: [26341]
    Other proteins in same PDB: d1hcgb_
10. Domain for 1ioe:
  - Domain d1ioea_: 1ioe A: [90667]
    Other proteins in same PDB: d1ioel_
    complexed with ca, xma
11. Domain for 1iqe:
  - Domain d1iqea_: 1iqe A: [90670]
    Other proteins in same PDB: d1iqel_
    complexed with ca, xmb
12. Domain for 1iqf:
  - Domain d1iqfa_: 1iqf A: [90672]
    Other proteins in same PDB: d1iqfl_
    complexed with ca, xmd
13. Domain for 1iqg:
  - Domain d1iqga_: 1iqg A: [90674]
    Other proteins in same PDB: d1iqgl_
    complexed with ca, xme
14. Domain for 1iqh:
  - Domain d1iqha_: 1iqh A: [90676]
    Other proteins in same PDB: d1iqhl_
    complexed with ca, xmf
15. Domain for 1iqi:
  - Domain d1iqia_: 1iqi A: [90678]
    Other proteins in same PDB: d1iqil_
    complexed with ca, xmg
16. Domain for 1iqj:
  - Domain d1iqja_: 1iqj A: [90680]
    Other proteins in same PDB: d1iqjl_
    complexed with ca, xmh
17. Domain for 1iqk:
  - Domain d1iqka_: 1iqk A: [90682]
    Other proteins in same PDB: d1iqkl_
    complexed with ca, xmi
18. Domain for 1iql:
  - Domain d1iqla_: 1iql A: [90684]
    Other proteins in same PDB: d1iqll_
    complexed with ca, xmj
19. Domain for 1iqm:
  - Domain d1iqma_: 1iqm A: [90686]
    Other proteins in same PDB: d1iqml_
    complexed with ca, xmk
20. Domain for 1iqn:
  - Domain d1iqna_: 1iqn A: [90688]
    Other proteins in same PDB: d1iqnl_
    complexed with ca, xmc
21. Domain for 1ksn:
  - Domain d1ksna_: 1ksn A: [72924]
    Other proteins in same PDB: d1ksnb_
    complexed with ca, fxv
22. Domain for 1kye:
  - Domain d1kyea_: 1kye A: [302640]
    Other proteins in same PDB: d1kyeb_
    automated match to d1fjsa_
    complexed with ca, rup
23. Domain for 1lpg:
  - Domain d1lpgb_: 1lpg B: [84667]
    Other proteins in same PDB: d1lpga_
    complexed with ca, ima
24. Domain for 1lpk:
  - Domain d1lpkb_: 1lpk B: [84669]
    Other proteins in same PDB: d1lpka_
    complexed with ca, cbb
25. Domain for 1lpz:
  - Domain d1lpzb_: 1lpz B: [84671]
    Other proteins in same PDB: d1lpza_
    complexed with ca, cmb
26. Domain for 1lqd:
  - Domain d1lqdb_: 1lqd B: [84677]
    Other proteins in same PDB: d1lqda_
    complexed with ca, cmi
27. Domain for 1mq5:
  - Domain d1mq5a_: 1mq5 A: [79400]
    Other proteins in same PDB: d1mq5l_
    complexed with ca, gol, xlc
28. Domain for 1mq6:
  - Domain d1mq6a_: 1mq6 A: [79402]
    Other proteins in same PDB: d1mq6l_
    complexed with ca, gol, xld
29. Domain for 1nfu:
  - Domain d1nfua_: 1nfu A: [80467]
    Other proteins in same PDB: d1nfub_
    complexed with ca, rrp
30. Domain for 1nfw:
  - Domain d1nfwa_: 1nfw A: [80469]
    Other proteins in same PDB: d1nfwb_
    complexed with ca, rrr
31. Domain for 1nfx:
  - Domain d1nfxa_: 1nfx A: [80471]
    Other proteins in same PDB: d1nfxb_
    complexed with ca, rdr
32. Domain for 1nfy:
  - Domain d1nfya_: 1nfy A: [80473]
    Other proteins in same PDB: d1nfyb_
    complexed with ca, rtr
33. Domain for 1p0s:
  - Domain d1p0sh_: 1p0s H: [93873]
    Other proteins in same PDB: d1p0se_, d1p0sl1, d1p0sl2
    complexed with mg, na
34. Domain for 1v3x:
  - Domain d1v3xa_: 1v3x A: [113506]
    Other proteins in same PDB: d1v3xb_
    complexed with ca, d76
35. Domain for 1xka:
  - Domain d1xkac_: 1xka C: [26344]
    Other proteins in same PDB: d1xkal1, d1xkal2
    complexed with 4pp, ca
36. Domains for 1xkb:
  1. Domain d1xkbc_: 1xkb C: [26342]
    Other proteins in same PDB: d1xkba1, d1xkba2, d1xkbb1, d1xkbb2
    complexed with 4pp, ca
  2. Domain d1xkbd_: 1xkb D: [26343]
    Other proteins in same PDB: d1xkba1, d1xkba2, d1xkbb1, d1xkbb2
    complexed with 4pp, ca
37. Domains for 2gd4:
  1. Domain d2gd4b1: 2gd4 B:16-249 [145192]
    Other proteins in same PDB: d2gd4a1, d2gd4c1, d2gd4i1, d2gd4l1
    complexed with ca, nag
  2. Domain d2gd4h1: 2gd4 H:16-244 [145194]
    Other proteins in same PDB: d2gd4a1, d2gd4c1, d2gd4i1, d2gd4l1
    automatically matched to 2GD4 B:16-249
    complexed with ca, nag
38. Domain for 2phb:
  - Domain d2phba_: 2phb A: [149464]
    Other proteins in same PDB: d2phbb_
    automated match to d1c5md_
    complexed with 230, ca
39. Domain for 2pr3:
  - Domain d2pr3a_: 2pr3 A: [149797]
    Other proteins in same PDB: d2pr3b_
    automated match to d1c5md_
    complexed with 237, ca
40. Domain for 2ra0:
  - Domain d2ra0a_: 2ra0 A: [151810]
    Other proteins in same PDB: d2ra0l_
    automated match to d1c5md_
    complexed with jnj
41. Domain for 3hpt:
  - Domain d3hptd_: 3hpt D: [191883]
    Other proteins in same PDB: d3hpta1, d3hpta2, d3hptb_, d3hptc1, d3hptc2
    automated match to d1c5md_
    complexed with act, ca, dms, gol, mes, na, yet
42. Domain for 3k9x:
  - Domain d3k9xd_: 3k9x D: [191888]
    Other proteins in same PDB: d3k9xa1, d3k9xa2, d3k9xb_, d3k9xc1, d3k9xc2
    automated match to d1c5md_
    complexed with ca, gol, mbm, na
43. Domain for 3kl6:
  - Domain d3kl6a_: 3kl6 A: [179423]
    Other proteins in same PDB: d3kl6b_
    automated match to d1c5md_
    complexed with 443, ca, edo
44. Domain for 3liw:
  - Domain d3liwa_: 3liw A: [180314]
    Other proteins in same PDB: d3liwb_
    complexed with ca, rup
45. Domain for 3sw2:
  - Domain d3sw2b_: 3sw2 B: [192087]
    Other proteins in same PDB: d3sw2a_
    automated match to d1c5md_
    complexed with ca, fi1, gol, na
46. Domains for 4bti:
  1. Domain d4btib_: 4bti B: [230000]
    Other proteins in same PDB: d4btia_, d4btie_
    automated match to d1p0sh_
    complexed with 7r9, ca
  2. Domain d4btif_: 4bti F: [230001]
    Other proteins in same PDB: d4btia_, d4btie_
    automated match to d1p0sh_
    complexed with 7r9, ca
47. Domains for 4btt:
  1. Domain d4bttb_: 4btt B: [229783]
    Other proteins in same PDB: d4btta_, d4btte_
    automated match to d1p0sh_
    complexed with ca, vyr
  2. Domain d4bttf_: 4btt F: [229784]
    Other proteins in same PDB: d4btta_, d4btte_
    automated match to d1p0sh_
    complexed with ca, vyr
48. Domains for 4btu:
  1. Domain d4btub_: 4btu B: [229782]
    Other proteins in same PDB: d4btua_, d4btue_
    automated match to d1p0sh_
    complexed with 6xs, ca
  2. Domain d4btuf_: 4btu F: [229785]
    Other proteins in same PDB: d4btua_, d4btue_
    automated match to d1p0sh_
    complexed with 6xs, ca
49. Domain for 4y6d:
  - Domain d4y6da_: 4y6d A: [277678]
    Other proteins in same PDB: d4y6db_
    automated match to d1lpgb_
    complexed with 48u
50. Domain for 4y71:
  - Domain d4y71a_: 4y71 A: [277679]
    Other proteins in same PDB: d4y71b_
    automated match to d1lpgb_
    complexed with 48w, ca
51. Domain for 4y76:
  - Domain d4y76a_: 4y76 A: [277680]
    Other proteins in same PDB: d4y76b_
    automated match to d1lpgb_
    complexed with 4o1, ca
52. Domain for 4y79:
  - Domain d4y79a_: 4y79 A: [277682]
    Other proteins in same PDB: d4y79b_
    automated match to d1lpgb_
    complexed with 4o6, ca, mg
53. Domain for 4y7a:
  - Domain d4y7aa_: 4y7a A: [277681]
    Other proteins in same PDB: d4y7ab_
    automated match to d1lpgb_
    complexed with 987, ca, mg
54. Domain for 4y7b:
  - Domain d4y7ba_: 4y7b A: [277683]
    Other proteins in same PDB: d4y7bb_
    automated match to d1lpgb_
    complexed with 44i, ca
55. Domain for 4zh8:
  - Domain d4zh8a_: 4zh8 A: [280588]
    Other proteins in same PDB: d4zh8b_
    automated match to d1lpgb_
    complexed with 4o4, ca
56. Domain for 4zha:
  - Domain d4zhaa_: 4zha A: [280593]
    Other proteins in same PDB: d4zhab_
    automated match to d1lpgb_
    complexed with 4o5, ca, mg
57. Domain for 5k0h:
  - Domain d5k0ha_: 5k0h A: [319429]
    Other proteins in same PDB: d5k0hb_
    automated match to d1fjsa_
    complexed with 6pk, ca
58. Domains for 7ahu:
  1. Domain d7ahuc_: 7ahu C: [417547]
    Other proteins in same PDB: d7ahua_, d7ahub_, d7ahud_, d7ahuf_, d7ahuh_, d7ahul_
    automated match to d1hcga_
    complexed with 0gj, ca
  2. Domain d7ahue_: 7ahu E: [417549]
    Other proteins in same PDB: d7ahua_, d7ahub_, d7ahud_, d7ahuf_, d7ahuh_, d7ahul_
    automated match to d1hcga_
    complexed with 0gj, ca

More info for Protein Coagulation factor Xa, protease domain from b.47.1.2: Eukaryotic proteases

Timeline for Protein Coagulation factor Xa, protease domain from b.47.1.2: Eukaryotic proteases:

Protein Coagulation factor Xa, protease domain from b.47.1.2: Eukaryotic proteases first appeared (with stable ids) in SCOP 1.55, called Protein Coagulation factor Xa (Chrismas factor), protease domain from b.47.1.2: Eukaryotic proteases
Protein Coagulation factor Xa, protease domain from b.47.1.2: Eukaryotic proteases appears in SCOPe 2.07