Lineage for Family b.43.3.1: Elongation factors

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 298343Fold b.43: Reductase/isomerase/elongation factor common domain [50412] (4 superfamilies)
    barrel, closed; n=6, S=10; greek-key
  4. 298354Superfamily b.43.3: Translation proteins [50447] (2 families) (S)
  5. 298355Family b.43.3.1: Elongation factors [50448] (6 proteins)

Proteins:

  1. 298356Elongation factor 2 (eEF-2), domain II [82118] (1 species)
  2. 298361Elongation factor eEF-1alpha, domain 2 [50454] (2 species)
    eukaryotic and archaeal homologue of EF-Tu
    1. 298362Species Archaeon Sulfolobus solfataricus [TaxId:2287] [69276] (1 PDB entry)
    2. 298365Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [50455] (4 PDB entries)
  3. 298370Elongation factor G (EF-G), domain II [50456] (1 species)
  4. 298377Elongation factor Tu (EF-Tu), domain 2 [50449] (4 species)
    N-terminal domain is related to G proteins; C-terminal domain is (6,10) barrel of circularly permuted topology
    1. 298378Species Cow (Bos taurus), mitochondrial [TaxId:9913] [50453] (1 PDB entry)
    2. 298383Species Escherichia coli [TaxId:562] [50450] (4 PDB entries)
    3. 298392Species Thermus aquaticus [TaxId:271] [50451] (4 PDB entries)
    4. 298401Species Thermus thermophilus [TaxId:274] [50452] (3 PDB entries)
  5. 298409Initiation factor eIF2 gamma subunit, domain II [74962] (1 species)
  6. 298416Initiation factor IF2/eIF5b, domains 2 and 4 [50458] (2 species)
    the C-terminal domain 4 has the same fold as domain 2; it probably binds fMet-tRNAfmet
    1. 298417Species Archaeon Methanobacterium thermoautotrophicum [TaxId:145262] [50459] (3 PDB entries)
    2. 298424Species Bacillus stearothermophilus [TaxId:1422] [50460] (1 PDB entry)

More info for Family b.43.3.1: Elongation factors

Timeline for Family b.43.3.1: Elongation factors: